Results 81 to 90 of about 5,636,748 (390)
Biological and Mechanical Limitations for Chronic Fast‐Scan Cyclic Voltammetry Sensor Design
Advanced Materials Technologies, EarlyView.Real‐time detection of neurochemicals has demonstrated value in the field of neuroscience. However, current methods have limitations for use in the chronic setting, which is often the ideal environment for research. This article discusses these limitations, as well as technologies that have been developed to overcome them, and provides recommendations ...
Mason L. Perillo +6 more
wiley +1 more source
Gambling and crime: An exploration of gambling availability and culture in an English prison
Criminal Behaviour and Mental Health, Volume 32, Issue 6, Page 389-403, December 2022., 2022 Abstract Background There is evidence that prisoners have the highest rate of problem gambling in any population, but little is known about the nature of in‐prison gambling, the motives for it or how it relates to prior gambling behaviour. Aims To investigate the prevalence and type of gambling prior to prison and the prevalence, type, and reasons for ...
Lauren Rebecca Smith +2 more
wiley +1 more source
Frontiers in Psychiatry, 2021 In this report, we present cross-sectional and longitudinal findings from single-voxel MEGA-PRESS MRS of GABA as well as Glu, and Glu + glutamine (Glx) concentrations in the ACC of treatment-seeking alcohol-dependent patients (ADPs) during detoxification
Guoying Wang +8 more
doaj +1 more source
Addiction, compulsion, and weakness of the will: A dual process perspective [PDF]
, 2016 How should addictive behavior be explained? In terms of neurobiological illness and compulsion, or as a choice made freely, even rationally, in the face of harmful social or psychological circumstances?
Henden, Edmund
core
Advanced Science, EarlyView.In situ Cell‐type‐specific proteome Analysis using antibody‐mediated Biotinylation (iCAB) is a method that directly targets and analyzes proteins in specific cell types within tissue. Applied to 5xFAD mice, iCAB identifies ≈8000 cell‐type‐specific proteins, revealing unique pathways in neurons, astrocytes, and microglia.
Taekyung Ryu +6 more
wiley +1 more source
Frontiers in Psychiatry, 2022 IntroductionConducted under the auspices of the Italian Society of Consultation Liaison Psychiatry (SIPC) the aim of this study was to describe the characteristics of Consultation Liaison Psychiatry (CLP) activity in Italy (SIPC-2—2018) over the past 20 ...
Luigi Zerbinati +45 more
doaj +1 more source
Generative artificial intelligence-enabled dynamic detection of nicotine-related circuits [PDF]
arXiv, 2022 The identification of addiction-related circuits is critical for explaining addiction processes and developing addiction treatments. And models of functional addiction circuits developed from functional imaging are an effective tool for discovering and verifying addiction circuits.
arxiv
Gaming addiction, definition, and measurement: a large-scale empirical study [PDF]
, 2013 Aims: Although the general public appears to have embraced the term 'video game addiction', the scientific debate as to whether 'gaming addiction' can actually be considered an addiction similar to substance addictions of DSM-IV is still unsettled. To
Griffiths, MD +3 more
core +1 more source
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
Advanced Science, EarlyView.The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari +20 more
wiley +1 more source
Kaohsiung Journal of Medical Sciences, 2012 Hyperactivation of glutamatergic N-methyl-D-aspartate (NMDA) receptors has been implicated in the excitotoxicity and pathophysiology of Parkinson's disease (PD).
Cornelius Rainer Pawlak +3 more
doaj +1 more source