Results 81 to 90 of about 10,174 (206)

‘I, Me, Myself’: Selfhood and Melancholy in the Journals of Gertrude Savile (1697–1758)

Journal for Eighteenth-Century Studies, EarlyView.
Abstract This article examines the journals of Gertrude Savile from 1727 in light of recent scholarship on early modern and eighteenth‐century melancholy. The concept had myriad associations with medicine, physiology, the imagination, and feeling, but questions remain about how melancholy during this period was considered by those outside the narrow ...
Daniel Beaumont
wiley   +1 more source

ACTH Stimulation Testing Is Often Unnecessary After Appropriate Patient Preparation Prior to Screening Cortisol Measurement

Clinical Endocrinology, EarlyView.
ABSTRACT Context Screening morning serum cortisol is used to select patients for ACTH stimulation testing to diagnose adrenal insufficiency (AI) but may be affected by pre‐analytical factors. Careful consideration to discontinue confounding medications beforehand may preclude the need for subsequent stimulation testing.
Christopher J. Symonds, Alexander A. Leung, Gregory A. Kline   +2 more
wiley   +1 more source

Erythema induratum of Bazin associated with Addison's disease: first description

São Paulo Medical Journal
CONTEXT: Erythema induratum of Bazin (EIB) is considered to be a tuberculid reaction and consists of recurrent painful nodules. The differential diagnosis includes diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum ...
Rodrigo Antonio Brandão Neto, Jozélio Freire de Carvalho   +1 more
doaj   +1 more source

HYPERPIGMENTATION AND ACTH – AN OVERVIEW OF LITERATURE [PDF]

Romanian Medical Journal, 2019
Introduction. ACTH (adrenocorticotropic hormone) is a key regulator of adrenal production involving cortisol as an essential hormone for life. The melanin is a pigment which is produced by melanocytes at the level of melanosomes (the melanogenesis ...
Florica Sandru, Mihai Cristian Dumitrascu, Simona Elena Albu, Mara Carsote, Ana Valea   +4 more
doaj   +1 more source

Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol [PDF]

, 2014
The plasma levels of high-density lipoprotein cholesterol (HDL) have an inverse relationship to the risks of atherosclerosis and cardiovascular disease, and have also been associated with longevity.
Borecki, Ingrid B, Christensen, Kaare, Feitosa, Mary F, Kammerer, Candace M, Kraja, Aldi T, Lee, Joseph H, Newman, Anne B, Province, Michael A, Straka, Robert, Wojczynski, Mary K   +9 more
core   +3 more sources

The Genetic Landscape of Hereditary Spastic Paraplegia in Greece

Clinical Genetics, EarlyView.
We investigated 112 Greek index‐cases with hereditary spastic paraplegia collected over > 25 years using NGS and MLPA. We identified a causative variant in 68 patients (60.7%), including 7 novel causative variants. This study presents a comprehensive overview of the phenotypic and genotypic spectrum of HSP in the Greek population.
Georgios Koutsis, Viorica Chelban, Chrisoula Kartanou, Zoi Kontogeorgiou, Chrysoula Koniari, Nikolaos Ragazos, Charalampos Voudommatis, Kristina Zhelcheska, David S. Lynch, Reza Maroofian, Ehsan Barkhordari, Rahema Mohammad, Ioannis Zaganas, Minas Drakos, Georgia Xiromerisiou, Efthymios Dardiotis, Leonidas Stefanis, Marios Panas, Henry Houlden, Georgia Karadima   +19 more
wiley   +1 more source

Levothyroxine sodium oral solution to control thyroid function in a patient with hypothyroidism and celiac disease

Clinical Case Reports, 2021
Implementing a gluten‐free diet and switching to the levothyroxine oral solution significantly improved malabsorptive and hypothyroid symptoms in a patient with hypothyroidism, Addison's disease, and celiac disease without the need to increase ...
Ernest Asamoah
doaj   +1 more source

Early menopause: A hazard to a woman's health [PDF]

, 2017
Early menopause or premature ovarian insufficiency (POI) is a common cause of infertility in women and affects about one per cent of young women. This disorder has significant psychological sequelae and major health implications.
Castelo-Branco Flores, Camil, Hernández Angeles, Claudio   +1 more
core   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Addison's disease and ACTH-producing pituitary microadenoma

Revista Médica del Hospital General de México, 2015
A 28-year-old man diagnosed with primary adrenal insufficiency (Addison's disease) in 2002. Following diagnosis, replacement therapy with hydrocortisone and fludrocortisone was indicated. Hydrocortisone replacement therapy was unsuccessful, and increased
S.S. Ortega, Y.H. Aguiar, P.P. Marrero, S.M. Casas   +3 more
doaj   +1 more source