Results 271 to 280 of about 22,797,050 (322)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A Multicatalytic Cascade for the Stereoselective Synthesis of 1,4-Chiral Nitro Alcohols. [PDF]

Org Lett
Ascaso-Alegre C, Linacero-Gracia Á, Ferreira P, Herrera RP, Mangas-Sánchez J.   +4 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Erratum: Addition to "Chemical Compensation Challenges in Processing Antiferroelectric PbZrO₃ Thin Films". [PDF]

ACS Omega
Haddad MH, Lebedev V, Holsgrove K, Rivera-Cruz S, Stock S, Maity N, Lisenkov S, Ponomareva I, Kumar A, Jones L, Bassiri-Gharb N.   +10 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Incorporation of mushroom powder: enhancing structure and flavor in pea-mung bean composite protein. [PDF]

NPJ Sci Food
Li Y, Ma S, Dong J, Cheng Z, Shen R.
europepmc   +1 more source

Study on the influence of anti stripping agent on the rheological properties of asphalt at high and low temperatures. [PDF]

PLoS One
Liu Q, Zhou F, Lei J, Zhao F.
europepmc   +1 more source

Influence of extrinsic skew scattering on the enhancement of anomalous Nernst coefficient in CoFe thin film by Cu-Ir addition

Aritra Ray
openalex   +1 more source

Evaluation of the effects of storage time, salt addition and type of additive on the fermentation, microbiological and organoleptic quality of Maralfalfa silage in Niger.

Maman Lawal Abdoul Aziz, Seydou Hamza Korombé, Djibo Ibrahim, Abdou Moussa Mahaman Maaouia, Aminatou Aliou Barazi, Amadou Abdoulaye M. Bahari, Mariama Gagara, Nourou Abdou, Soumana Gouro Abdoulaye   +8 more
openalex   +1 more source