Safety and efficacy of a feed additive consisting of <i>Lactobacillus acidophilus</i>CNCM I-3231, <i>Ligilactobacillus salivarius</i>CNCM I-3233, <i>Lacticaseibacillus paracasei</i>CNCM I-4901, <i>Bifidobacterium longum</i>CNCM I-3227 and <i>Bifidobacterium animalis</i> subsp. <i>lactis</i>CNCM I-3993 (FlorEquilibre® Chat) for cats (WAMINE SAS). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +24 more
europepmc +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Predicting maize hybrid performance with machine learning and a locus-specific weighted degree of dominance transformation. [PDF]
Osatohanmwen BE +5 more
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride produced with <i>Corynebacterium glutamicum</i>CGMCC 23982 for all animal species (Eppen Europe SAS). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +20 more
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Assessment of the feed additive consisting of astaxanthin (2a161j) for fish, crustaceans and ornamental fish for the renewal of its authorisation (BASF SE, DSM Nutritional Products Ltd., JYB Europe BV, NHU EUROPE GmbH). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +27 more
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Role of Solid Additives in Morphological and Structural Optimization of Bulk Heterojunction Organic Solar Cells. [PDF]
Khan MR, Jarząbek B, Ullah A.
europepmc +1 more source

