Results 261 to 270 of about 881,399 (312)

Edge-focused wire arc additive manufacturing: Method development with ANN-based stress-strain and mass-efficiency. [PDF]

PLoS One
Hong Ngoc TL, Xuan Chi HT, Nguyen VT, Son Minh P.   +3 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of an extract from the dried leaves of <i>Hedera helix</i> L. (common ivy extract) and thymol for all animal species and categories except poultry, ornamental birds and all aquatic animal species (FEFANA asbl). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Theodoridou K, Bastos ML, Benfenati E, Brantom P, Chesson A, Schlatter J, Westendorf J, Manini P, Dusemund B.   +22 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Effects of Ligilactobacillus agilis W70 and dietary protein levels on feed efficiency, nitrogen metabolism, and rumen microbiota of lactating dairy cows. [PDF]

Anim Microbiome
Duan X, Ma L, Bridson C, Luo Z, Vigors S, Bu D.   +5 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

6. Industriekolloquium des Sonderforschungsbereichs 814 - Additive Fertigung additive Fertigung - individuell, innovativ, intersdisziplinär

, 2018
Sonderforschungsbereich 814 - Additive Fertigung 2018 Nürnberg, Drummer, Dietmar 1971-, Friedrich-Alexander-Universität Erlangen-Nürnberg   +2 more
core  

Antimicrobial and Synergistic Activity of Metformin Against <i>Helicobacter pylori</i>. [PDF]

Can J Infect Dis Med Microbiol
Rajab WH, Jaradat N, Abdo Q, Aljouda N, Qadi M.   +4 more
europepmc   +1 more source

Integrating line × tester analysis and GGE biplot to identify superior sweet corn hybrids in tropical environments. [PDF]

PeerJ
Ruswandi D, Ismail A, Persada GS, Fauzan MR, Syihab FN, Yuwariah Y.   +5 more
europepmc   +1 more source

Food Coloring Additives and Incidence of Type 2 Diabetes in the NutriNet-Santé Prospective Cohort. [PDF]

Diabetes Care
Shah S, Hasenböhler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Yvroud P, Agaësse C, De Sa A, Huybrechts I, Pierre F, Audebert M, Coumoul X, Julia C, Kesse-Guyot E, Allès B, Deschamps V, Hercberg S, Chassaing B, Cosson E, Tatulashvili S, Deschasaux-Tanguy M, Srour B, Touvier M.   +22 more
europepmc   +1 more source