Results 161 to 170 of about 1,035,528 (296)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

BayesX: Analyzing Bayesian Structural Additive Regression Models [PDF]

There has been much recent interest in Bayesian inference for generalized additive and related models. The increasing popularity of Bayesian methods for these and other model classes is mainly caused by the introduction of Markov chain Monte Carlo (MCMC)
Andreas Brezger, Stefan Lang, Thomas Kneib   +2 more
core  

Metabolic and Candidate Genetic Factors Associated with Overweight/Obesity in Patients of Kazakh Ethnicity with Psoriasis: A Cross-Sectional Study. [PDF]

Medicina (Kaunas)
Zhumabekova B, Svyatova G, Askarova G, Akanov Z, Baltabaev MA, Ge A, Dzhumabekov A, Berdiyarova G, Baisultanova A, Issakova G.   +9 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Next-generation microneedle patches for transdermal therapeutics and diagnostics. [PDF]

Discov Nano
Chen TH, Hsu MT, Lee KH, Karmakar R, Mukundan A, Kuzhali SS, Chou CK, Lin WS, Wang HC.   +8 more
europepmc   +1 more source

Matrix approach to consistency of the additive efficient normalization of semivalues

, 2007
In fact the Shapley value is the unique efficient semivalue. This motivated Ruiz et al. to do additive efficient normalization for semivalues. In this paper, by matrix approach we derive the relationship between the additive efficient normalization of semivalues and the Shapley value.
Xu, Genjiu, Driessen, Theodorus Stephanus Hubertus, Sun, H.   +2 more
openaire   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Leakage-Controlled and Information-Bounded Evaluation of Multi-Task Learning for Crumb-Rubber Modified Asphalt: What Twenty Mix Designs Can and Cannot Support. [PDF]

Materials (Basel)
Huang H, Gao Y, Tian B, Yang Z.
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Appraisal Using Generalized Additive Models [PDF]

Many of the results from real estate empirical studies depend upon using a correct functional form for their validity. Unfortunately, common parametric statistical tools cannot easily control for the possibility of misspecification.
R. Kelley Pace
core