Results 101 to 110 of about 4,477,780 (283)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

New Formulas of Feedback Capacity for AGN Channels with Memory: A Time-Domain Sufficient Statistic Approach

open access: yesEntropy
Recently, several papers identified technical issues related to equivalent time-domain and frequency-domain “characterization of the n–block or transmission” feedback capacity formula and its asymptotic limit, the feedback capacity, of additive Gaussian ...
Charalambos D. Charalambous   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

On the Nonlocal Fractional Delta-Nabla Sum Boundary Value Problem for Sequential Fractional Delta-Nabla Sum-Difference Equations

open access: yes, 2020
In this paper, we propose sequential fractional delta-nabla sum-difference equations with nonlocal fractional delta-nabla sum boundary conditions.
Jiraporn Reunsumrit   +1 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Jupiter Additive Difference [of the Equation of Anomaly] - Ptolemy's Almagest by Toomer (Gerald J.) (1984) | Type-B (ID n° 361)

open access: yes, 2021
This is a type B edition: A type-B edition corresponds to a critical edition of several table witnesses: it is based on several different editions, themselves based on tables from different primary sources. A type-B edition can be based on type-A, type-B or type-C editions.
openaire   +2 more sources

h-Stability of Nonlinear Hilfer Nabla Fractional Difference Equations

open access: yes
This paper investigates the h-stability of nonlinear Hilfer nabla fractional difference equations, which interpolate between the Riemann–Liouville and Caputo nabla fractional differences through an additional type parameter.
Jagan Mohan Jonnalagadda   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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