Results 51 to 60 of about 36,200 (257)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Stability Analysis of A-Quartic Functional Equation
, 2021 In this paper, we study the general solution of the functional equation, which is derived from additive–quartic mappings. In addition, we establish the generalized Hyers–Ulam stability of the additive–quartic functional equation in Banach spaces by using
Vediyappan Govindan +5 more
core +1 more source
Fuzzy stability results of additive functional equation in different approaches
, 2020 In this paper, we investigate some stability results of the following finite dimensional additive functional equation f Xn i=1 kxi ! + Xn j=1 f −kxj + Xn i=1;i6=j kxi = (n − 1) "Xn i=1 (2i − 1)f(xi) # where n is the positive integer with N − {0, 1, 2} and k is the only odd positive integers, in Fuzzy Normed space using direct and fixed point ...
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Weighted estimating equations for additive hazards models with missing covariates [PDF]
, 2018 This paper presents simple weighted and fully augmented weighted estimators for the additive hazards model with missing covariates when they are missing at random.
Lihong Qi +9 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Random attractors for stochastic lattice systems with non-Lipschitz non-linearity [PDF]
, 2012 In this paper we study the asymptotic behaviour of solutions of a first-order stochastic lattice dynamical system with an additive noise. We do not assume any Lipschitz condition on the nonlinear term, just a continuity assumption together with growth
Caraballo Garrido, Tomás +2 more
core +1 more source