Results 61 to 70 of about 4,477,780 (283)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Finite difference methods for coupled flow interaction transport models
Understanding chemical transport in blood flow involves coupling the chemical transport process with flow equations describing the blood and plasma in the membrane wall.
Shelly McGee, Padmanabhan Seshaiyer
doaj
Synthesis of band-pass discrete filters
Background. The article considers the synthesis of complex and real discrete band-rejection filters (BRRFs) that provide simultaneous processing of an additive mixture of useful and interfering signals coming from the output of a radar receiver.
Sergey I. Ziatdinov +1 more
doaj +1 more source
Advances in Difference Equations
The aim of this reprint is to highlight the significance of difference equations and their applications in applied mathematics. Difference equations provide a robust and widely recognized framework for modeling complex dynamical systems. In recent years,
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Impact of social inequalities at birth on the longevity of children born 1914-1916: A cohort study.
BackgroundTesting whether familial socioeconomic status (SES) in childhood is a predictor of mortality has rarely been done on historical cohorts.MethodsThe birth certificates of 4,805 individuals born 1914-1916 in 16 districts of the Paris region were ...
Nicolas Todd +3 more
doaj +1 more source

