Results 121 to 130 of about 373,315 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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A note on additive functions [PDF]
Pacific Journal of Mathematics, 1957 Delange, H., Halberstam, H.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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, 2012 Quantile regression allows to model the complete conditional distribution of a response variable - expressed by its quantiles - depending on covariates, and thereby extends classical regression models which mainly address the conditional mean of a ...
Fenske, Nora
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Veterinary and Animal ScienceA commercial dairy farm with two dairy units (about 3000 cows each), similar management and diets was used to evaluate the effect of a feed additive based on a mix of condense and hydrolysable tannins (ByPro®) on lactating cow services per conception and
Alejandro R Castillo +2 more
doaj +1 more source
Polylinear Additive Functionals of Superprocesses
Journal of Functional Analysis, 1997 The author has already studied the linear additive functionals of superprocesses in a previous work [Trans. Am. Math. Soc. 314, No. 1, 255-282 (1989; Zbl 0674.60070)]. But the study of self-intersection local times and \(k\)-multiple points of superprocesses raised the question of polylinear additive functionals.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
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