Results 141 to 150 of about 5,901,052 (252)

The Cox-Aalen Rate Model for Recurrent Events With an Informative Terminal Event. [PDF]

Stat Med
Yue M, Chen X, Chen J, Sun L.
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effects of concurrent neuropathologies with Alzheimer disease neuropathologic change on cognitive decline: Minimal impact of vascular brain injury compared with other combinations. [PDF]

J Neuropathol Exp Neurol
Yasuda SM, Mock C, Gauthreaux K, Chan KCG, Keene CD, Culhane JE, Chen YC, Kukull W.   +7 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

A Representation of Preferences by the Choquet Integral with Respect to a 2-Additive Capacity [PDF]

In the context of Multiple criteria decision analysis, we present the necessary and sufficient conditions allowing to represent an ordinal preferential information provided by the decision maker by a Choquet integral w.r.t a 2-additive capacity.
Michel Grabisch, Christophe Labreuche, Brice Mayag   +2 more
core  

Revisiting additive and dominance effects. [PDF]

G3 (Bethesda)
Endelman JB, Dawson JC.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

An Algorithm for Clustered Data Generalized Additive Modelling with S-PLUS [PDF]

We present a set of functions in S-PLUS to implement the clustered data generalized additive marginal modelling (CDGAM) strategy proposed by Berhane and Tibshirani (1998).
Vincent Carey, Lin Yee Hin
core  

Evaporation Kinetics Engineering Suppressed Bimolecular Recombination in All-Polymer Solar Cells. [PDF]

Adv Sci (Weinh)
Feng D, Mei L, Li C, Fu Y, Liu H, Xu L, Chan PF, Yang Z, Wang Y, Su CJ, Jeng US, Fong PW, Zuo L, Li G, Yan H, Wu J, Chen XK, Lu X.   +17 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source