Results 161 to 170 of about 373,315 (309)
An Algorithm for Clustered Data Generalized Additive Modelling with S-PLUS
We present a set of functions in S-PLUS to implement the clustered data generalized additive marginal modelling (CDGAM) strategy proposed by Berhane and Tibshirani (1998).
Vincent Carey, Lin Yee Hin
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Proceedings of the American Mathematical Society, 1969 Friedman, N. A., Katz, Melvin
openaire +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Zero-inflation problem is very common in ecological studies as well as other areas. Nonparametric regression with zero-inflated data may be studied via the zero-inflated generalized additive model (ZIGAM), which assumes that the zero-inflated responses ...
Kung-Sik Chan, Hai Liu
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Development of a Confined-Space Suitability Index (CSSI) using Least Absolute Shrinkage and Selection Operator (LASSO) regression: a pilot study for structured fitness-for-duty screening. [PDF]
PLoS OneLee I, Hong S, Jang E, Lee J, Lee J.
europepmc +1 more source
Global Bahadur representation for nonparametric censored regression quantiles and its applications [PDF]
This paper is concerned with the nonparametric estimation of regression quantiles where the response variable is randomly censored. Using results on the strong uniform convergence of U-processes, we derive a global Bahadur representation for the weighted
Yingcun Xia, Oliver Linton, Efang Kong
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source