Results 191 to 200 of about 124,550 (275)

4D-ONIX for reconstructing 3D movies from sparse X-ray projections via deep learning. [PDF]

Commun Eng
Zhang Y, Yao Z, Klöfkorn R, Ritschel T, Villanueva-Perez P.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Efficiency Comparison of Reduced Graphene Oxide (rGO) Composite-Incorporated Polyacrylonitrile Nanofibrous Filters for Respirable Crystalline Silica Dust and Coal Dust. [PDF]

ACS Omega
Moradi M, Kakoria A, Zheng L, Xu G.
europepmc   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

The application of pre-trained large visual-language models for preliminary diagnosis of esophageal whitish plaques in large-scale esophageal cancer screening. [PDF]

NPJ Precis Oncol
Li Y, Li X, Zhang D, Zhu W, Hu Y, Zhao Z, Zhao Q.   +6 more
europepmc   +1 more source

Generation of Permutations by Addition [PDF]

Mathematics of Computation, 1962
openaire   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Electroactive interface-enhanced dielectric elastomer with ultrahigh electroadhesion and multifunctional droplet actuation. [PDF]

Sci Adv
Yan H, Zhang J, Liu L, Wei C, Zhang C, Wang K, Zhu J, Moumni Z, Zhang W, Lu J.   +9 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

GAN-based bone suppression using a combined loss function. [PDF]

Front Artif Intell
Jochymek L, Vašinková M, Doleží V, Gajdoš P.   +3 more
europepmc   +1 more source