Results 121 to 130 of about 33,834 (307)

Advancing Sustainable Decision Making in Additive Manufacturing: A Comprehensive Review of Multi-Criteria Decision Making Approaches

Clean Technologies
Additive manufacturing (AM) is one of the technologies of Industry 4.0 that has been contributing to the development of different manufacturing industries.
Adriana S. F. Alves, J. P. Oliveira, Radu Godina   +2 more
doaj   +1 more source

Simulation of additive manufacturing using coupled constitutive and microstructure models

, 2016
The paper describes the application of modeling approaches used in Computational Welding Mechanics (CWM) applicable for simulating Additive Manufacturing (AM).
Lindgren, Lars-Erik,, Lundbäck, Andreas,, Andersson, Joel,, Fisk, Martin,, Pederson, Robert,   +4 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Additive Manufacturing – Process Optimisation

Additive Manufacturing (AM), often known as 3D printing, is a vast discipline with a wide range of applications and approaches, all of which provide unique contributions to the development of this rapidly evolving field.

core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Additive Manufacturing of Ceramics Study: Sustainable Material Extrusion and Its Potential Role in Circular Economy

Applied Sciences
Additive Manufacturing (AM) has emerged as a transformative technology enabling the production of complex geometries and customized components with minimal material waste.
Paula González-Suárez, Pedro Manuel Hernández-Castellano, Annabella Narganes-Pineda   +2 more
doaj   +1 more source

Infusing Additive Manufacturing Education with Applications: An Industry-Centric Approach

, 2014
This paper details how Nanyang Polytechnic has applied industry-centric approach in training its students and industry personnel with relevant additive manufacturing technologies infused with real industry applications.
David S. K. Wong, Wong, David S. K.
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Advances in Additive Manufacturing and Their Applications (2nd Edition)

This Special Issue presents ten original research articles that explore key challenges and innovative solutions in Additive Manufacturing (AM) for metallic applications.

core   +1 more source

Bio Cad Modeling of Customized Exoskeleton for Rehabilitation of Myopathies and its Fabrication Using Additive Manufacturing

, 2014
Additive Manufacturing (AM) is a process of joining materials to make objects from 3D model data, usually layer upon layer, as opposed to subtractive manufacturing methodologies [1].
P. Balamurugan, Balamurugan, P., Arumaikkannu, G., G. Arumaikkannu   +3 more
core   +1 more source