Results 31 to 40 of about 17,462 (263)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Current options in the life cycle assessment of additive manufacturing products
Open Engineering, 2019 Additive manufacturing (AM) is a manufacturing process that allows for the creation of a physical object from a digital model. Additive manufacturing has a number of advantages over the conventional methods, inter alia the production of very complex ...
Výtisk Jan +3 more
doaj +1 more source
Materials & Design, 2019 As the application of additive manufacturing (AM) reaches an unprecedented scale in both academia and industry, a reflection upon the state-of-the-art developments in the design for additive manufacturing (DfAM) and structural optimisation, becomes vital
János Plocher, Ajit Panesar
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
AM Envelope. The potential of Additive Manufacturing for facade constructions
A+BE | Architecture and the Built Environment, 2013 This dissertation shows the potential of Additive Manufacturing (AM) for the development of building envelopes: AM will change the way of designing facades, how we engineer and produce them. To achieve today’s demands from those future envelopes, we have to find new solutions.New technologies offer one possible way to do so. They open new approaches in
openaire +4 more sources
MetalsIn recent years, additive manufacturing (AM) has played a significant role in various fashion industries, especially the textile and jewelry manufacturing sectors.
Geethapriyan Thangamani +7 more
doaj +1 more source
A Review of Additive Manufacturing of Soft Magnetic Materials in Electrical Machines
Machines, 2023 This paper presents a review of the main advantages and challenges of Additive Manufacturing (AM) applied in the production of soft magnetic components for electrical machines.
Nicola Giannotta +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Design and manufacture of life size human model using material extrusion and vat photopolymerization additive processes [PDF]
MATEC Web of Conferences, 2019 Nowadays, Additive Manufacturing (AM) is increasingly being used in various fields of medicine. Using Material Extrusion additive process – Fused Filament Fabrication (FFF) method are produced 3D models of organs or body parts designed for preoperative ...
Molnar Ivan +4 more
doaj +1 more source