Results 41 to 50 of about 128,882 (238)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Current options in the life cycle assessment of additive manufacturing products

Open Engineering, 2019
Additive manufacturing (AM) is a manufacturing process that allows for the creation of a physical object from a digital model. Additive manufacturing has a number of advantages over the conventional methods, inter alia the production of very complex ...
Výtisk Jan, Kočí Vladimír, Honus Stanislav, Vrtek Mojmír   +3 more
doaj   +1 more source

Self-supporting structure design in additive manufacturing through explicit topology optimization

, 2017
One of the challenging issues in additive manufacturing (AM) oriented topology optimization is how to design structures that are self-supportive in a manufacture process without introducing additional supporting materials. In the present contribution, it
Du, Zongliang, Guo, Xu, Liu, Chang, Liu, Ying, Zhang, Weisheng, Zhou, Jianhua   +5 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

A Comprehensive Review of Laser Powder Bed Fusion in Jewelry: Technologies, Materials, and Post-Processing with Future Perspective

Metals
In recent years, additive manufacturing (AM) has played a significant role in various fashion industries, especially the textile and jewelry manufacturing sectors.
Geethapriyan Thangamani, Stefano Felicioni, Elisa Padovano, Sara Biamino, Mariangela Lombardi, Daniele Ugues, Paolo Fino, Federica Bondioli   +7 more
doaj   +1 more source

Hybrid manufacturing – integrating traditional manufacturers with additive manufacturing (AM) supply chain

Additive Manufacturing, 2018
Abstract The ever-growing applications of Additive Manufacturing (AM) in the production of low volume- high value metal parts can be attributed to improving AM processing capabilities and complex design freedom. However, secondary post-processing using traditional processes such as machining, grinding, heat treatment and hot isostatic pressing, i.e.,
Danielle Strong, Michael Kay, Brett Conner, Thomas Wakefield, Guha Manogharan   +4 more
openaire   +1 more source

Multiscale, thermomechanical topology optimization of self-supporting cellular structures for porous injection molds [PDF]

, 2018
Purpose This paper aims to establish a multiscale topology optimization method for the optimal design of non-periodic, self-supporting cellular structures subjected to thermo-mechanical loads.
Tovar, Andres, Wu, Tong
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A Review of Additive Manufacturing of Soft Magnetic Materials in Electrical Machines

Machines, 2023
This paper presents a review of the main advantages and challenges of Additive Manufacturing (AM) applied in the production of soft magnetic components for electrical machines.
Nicola Giannotta, Giada Sala, Claudio Bianchini, Ambra Torreggiani   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source