Results 71 to 80 of about 110,390 (311)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Additive k-Dimensional Inset Entropies with Measurable Sum Property

open access: yes, 1994
This paper culminates a main line of research on additive sum form measures of information, to which many authors have contributed. We determine all measures of inset information, depending on any number of discrete probability distributions, which are ...
Ebanks, B.R.
core   +1 more source

Additive manufactured versus traditional osteosynthesis plates - A finite element analysis

open access: yes, 2022
Additive Manufacturing (AM) is rapidly gaining acceptance in healthcare. Its use enables the design and production of more complex geometries than traditional subtractive manufacturing does with specific materials such as polyetheretherketone (PEEK). For
Barth, Tobias   +5 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Tribological Property of Nano-Cu as Additive in Lubricating Oil

open access: yes, 2011
The tribological property of nano-Cu as additive in lubricating oil was investigated on a stock-on-ring testing machine. Friction coefficient and wear mass loss were discussed in order to study tribological property.
Xu Rui Gao, Shun Xing Wang
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Legal Aspects of Protecting Intellectual Property in Additive Manufacturing

open access: yes, 2016
Part 1: THEMES AND ISSUESInternational audienceAdditive manufacturing has emerged as a transformative technology that will play a significant role in the future.
Todd Andel   +7 more
core   +1 more source

Modeling Probabilities of Patent Oppositions in a Bayesian Semiparametric Regression Framework [PDF]

open access: yes, 2003
Most econometric analyses of patent data rely on regression methods using a parametric form of the predictor for modeling the dependence of the response given certain covariates.
Jerak, A.   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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