Results 91 to 100 of about 13,197,921 (301)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A. Pushkin's Address 'To a Kalmyk Maiden' as a Historical-Literary Problem
Oriental Studies, 2018 Since its publication and especially after the release of “Journey to Erzurum…”, A.Pushkin's address “To a Kalmyk Maiden” has belonged to several most essential spheres of Pushkin’s literary system, appearing in most complex correlation with both his ...
B. Kichikova
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
RESPONSE TO ADDRESS OF WELCOME AND PRESIDENTʼS ADDRESS [PDF]
AJN, American Journal of Nursing, 1913 n ...
openaire +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
More Than One Encounter: Exploring the Second-Person Perspective and the In-Between
Open PhilosophyIn this essay, I explore the notion of the encounter as a challenge to the second-person perspective. I do so by turning to Jacques Derrida’s account of the encounter with the associated notions of address, second-person perspective, otherness, and the ...
Hansen Bjarke Mørkøre Stigel
doaj +1 more source