Results 111 to 120 of about 6,726,151 (303)
Microwave photonic sensor systems represent a wide class of information systems with measurement conversion that use standardized analog and parallel links of parallel and sequential type with filtering, allowing to functionally displaying the ...
A.Zh. Sakhabutdinov, O.G. Morozov
doaj
RESPONSE TO ADDRESS OF WELCOME AND PRESIDENTʼS ADDRESS [PDF]
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openaire +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
More Than One Encounter: Exploring the Second-Person Perspective and the In-Between
In this essay, I explore the notion of the encounter as a challenge to the second-person perspective. I do so by turning to Jacques Derrida’s account of the encounter with the associated notions of address, second-person perspective, otherness, and the ...
Hansen Bjarke Mørkøre Stigel
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
We present a method for unsupervised topic modelling which adapts methods used in document classification (Blei et al., 2003; Griffiths and Steyvers, 2004) to unsegmented multi-party discourse transcripts.
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Illuminated address presented to Sir Robert William Chapman [PDF]
Illuminated address presented to Sir Robert William Chapman by his peers and students ‘in recognition of the fiftieth year of your invaluable services on the teaching staff of the University of Adelaide, first as lecturer and for thirty years as ...
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