Results 151 to 160 of about 83,570 (309)

Is explaining more like showing or more like building?-Agency in metaphors of explaining. [PDF]

Front Psychol
Porwol P, Scharlau I.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

The impact of COVID-19 on the well-being of general practitioners and trainees is multifacated and requires intensive diagnostic efforts. [PDF]

J Family Med Prim Care
Finsterer J.
europepmc   +1 more source

Spatial communication systems across languages reflect universal action constraints. [PDF]

Nat Hum Behav, 2023
Coventry KR, Gudde HB, Diessel H, Collier J, Guijarro-Fuentes P, Vulchanova M, Vulchanov V, Todisco E, Reile M, Breunesse M, Plado H, Bohnemeyer J, Bsili R, Caldano M, Dekova R, Donelson K, Forker D, Park Y, Pathak LS, Peeters D, Pizzuto G, Serhan B, Apse L, Hesse F, Hoang L, Hoang P, Igari Y, Kapiley K, Haupt-Khutsishvili T, Kolding S, Priiki K, Mačiukaitytė I, Mohite V, Nahkola T, Tsoi SY, Williams S, Yasuda S, Cangelosi A, Duñabeitia JA, Mishra RK, Rocca R, Šķilters J, Wallentin M, Žilinskaitė-Šinkūnienė E, Incel OD.   +44 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Children Sustain Their Attention on Spatial Scenes When Planning to Describe Spatial Relations Multimodally in Speech and Gesture. [PDF]

Dev Sci
Ünal E, Karadöller DZ, Özyürek A.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Variation and change in pronominal address in 19th and early 20th-century German private letters. [PDF]

J Hist Socioling
Schiegg M, Elspaß S.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source