Results 81 to 90 of about 1,158,157 (263)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Understanding the economic impacts of climate change is crucial for shaping effective policy responses. This study examines the relationship between historical temperature fluctuations and economic growth in Chinese cities from 1999 to 2018.
Yu Song +7 more
doaj +1 more source
Spouses addressing their parents-in-law in Russian culture [PDF]
The paper examines the forms of addressing the nearest in-law relatives existing in Russian family communication. Addresses to family members are among the oldest means of appealing and are marked by national identity in any culture.
Krilova, Irina Александровна +1 more
doaj +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The regional climate over China has changed pronouncedly since the mid-20th, posing substantial risks and uncertainties to local crop production. The maize production has demonstrated considerable sensitivity to such changes. Observations in recent years
Na Huang +10 more
doaj +1 more source
مستقبل الحاسبات الالكترونية في التعليم
نتائج بحث لتقييم أداء بعض أساليب تنظيم المعلومات للوصول المباشر باستعمال العنونة التحتية (Hach Addressing) من خلال تطبيقها على ملفات نموذجية للمفاتيح Sample Keys Files) تم اختيارها من الواقع التطبيقي لأنظمة مهمة في قطرنا .
ندى عبد علي
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source

