Results 251 to 260 of about 91,759 (348)

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

open access: yesAngewandte Chemie, EarlyView.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach   +4 more
wiley   +1 more source

Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity

open access: yesAngewandte Chemie, EarlyView.
This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte   +2 more
wiley   +1 more source

Nickel‐Catalyzed Enantioconvergent Arylation of Unactivated Cyclic Electrophiles: Asymmetric Synthesis of 3‐Substituted Pyrrolidines

open access: yesAngewandte Chemie, EarlyView.
Metal‐catalyzed enantioconvergent substitutions of unactivated cyclic electrophiles by organometallic nucleophiles have not previously been reported. Herein, a chiral nickel catalyst is described that achieves this objective, coupling 3‐iodopyrrolidine derivatives with arylzinc nucleophiles.
Ting Hei Matthew Wong   +2 more
wiley   +1 more source

Legged Locomotion in Lattices: Centipede Traversal of Obstacle-Rich Environments. [PDF]

open access: yesAnn N Y Acad Sci
Pierce CJ   +6 more
europepmc   +1 more source

Structurally Constrained Stibenium: Metallomimetic C−Si Bond Activation

open access: yesAngewandte Chemie, EarlyView.
A structurally constrained stibenium cation supported by a 2,6‐bis(o‐carborano)pyridine pincer‐type ligand was prepared, and its preliminary reactivity toward silanes was investigated. Remarkably, Si−C bonds in silanes undergo activation via an oxidative‐addition‐type process at the cationic Sb center.
Donia Toami, Roman Dobrovetsky
wiley   +1 more source

3D-printed shoe soles with structural properties towards reducing knee adduction moments during walking. [PDF]

open access: yesFront Bioeng Biotechnol
Jiang Z   +6 more
europepmc   +1 more source

Azide‐to‐Diazo Transformation Facilitated by Michael Addition via Phosphazide Formation

open access: yesAngewandte Chemie, EarlyView.
A new type of Michael addition based on azide‐to‐diazo conversion is disclosed. This unusual transformation proceeds via 1,4‐addition accompanied by N─N bond cleavage of phosphazide intermediates under practical conditions. The high versatility of the resulting Michael adducts enables the synthesis of a wide variety of organonitrogen compounds ...
Tomoki Mano   +3 more
wiley   +1 more source

Humanoid Robotic Loading Enhances Mechanotransduction in Tendon Tissue Engineering. [PDF]

open access: yesCyborg Bionic Syst
Liu Z   +13 more
europepmc   +1 more source

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