BackgroundAcute and chronic exposures to widely used organophosphorus (OP) insecticides are common. Children\u2019s detoxification mechanisms are not well developed until several years after birth.
core
DNA adductomics: Method development and integration in biological effect monitoring
, 2023 Environmental omics can provide informative biomarkers for identifying pathologies or physiological responses to environmental change. Nucleic acid adductomics, one of the newest omics techniques, is particularly well suited for assessing exposure and effects of environmental contaminants because the technique can capture modifications at the (epi ...
openaire +1 more source
Recent advances in mass spectrometry-based computational metabolomics. [PDF]
Curr Opin Chem Biol, 2023 Ebbels TMD +6 more
europepmc +1 more source
Pathways to Identify Electrophiles In Vivo Using Hemoglobin Adducts: Hydroxypropanoic Acid Valine Adduct and Its Possible Precursors. [PDF]
Chem Res Toxicol, 2022 Vryonidis E +7 more
europepmc +1 more source
Mass Spectrometry-Based Methodologies for Targeted and Untargeted Identification of Protein Covalent Adducts (Adductomics): Current Status and Challenges [PDF]
, 2019 João Nunes +5 more
openalex +1 more source
Rates of preterm birth and low birthweight continue to rise in the United States and pose a significant public health problem. Although a variety of environmental exposures are known to contribute to these and other adverse birth outcomes, there has been
core
Using Biomarkers to Characterize Exposures to Diesel Exhaust and Smoky Coal [PDF]
Ambient air pollution and household air pollution are among the leading causes of mortality, responsible for 6 million premature deaths per year globally.
Lu, Sixin Samantha
core
Exposure to diesel engine exhaust and alterations to the Cys34/Lys525 adductome of human serum albumin. [PDF]
Environ Toxicol Pharmacol, 2022 Wong JYY +29 more
europepmc +1 more source
As the number of nanomaterial workers increase there is need to consider whether biomonitoring of exposure should be used as a routine risk management tool. Currently, no biomonitoring of nanomaterials is mandated by authoritative or regulatory agencies.
core
Biomonitoring of Ambient Outdoor Air Pollutant Exposure in Humans Using Targeted Serum Albumin Adductomics. [PDF]
Chem Res Toxicol, 2021 Smith JW +6 more
europepmc +1 more source