Results 11 to 20 of about 199,850 (190)

Correlation Investigation between Pyrrole-DNA and Pyrrole-Protein Adducts in Male ICR Mice Exposed to Retrorsine, a Hepatotoxic Pyrrolizidine Alkaloid

open access: yesToxins, 2022
Pyrrolizidine alkaloids (PAs) have been found in over 6000 plants worldwide and represent the most common hepatotoxic phytotoxins. Catalyzed by hepatic cytochrome P450 enzymes, PAs are metabolized into reactive pyrrolic metabolites, which can alkylate ...
Lin Zhu   +5 more
doaj   +1 more source

A Theoretical and Experimental Study on the Lewis Acid−Base Adducts (P4E3)·(BX3) (E = S, Se; X = Br, I) and (P4Se3)·(NbCl5) [PDF]

open access: yes, 2001
The Lewis acid−base adducts (P4E3)·(BX3) (E = S, Se; X = Br, I) and (P4Se3)·(NbCl5) have been prepared and characterized by Raman, IR, and solid-state 31P MAS NMR spectroscopy. Hybrid density functional calculations (B3LYP) have been carried out for both
Aubauer, Christoph   +5 more
core   +1 more source

Estimativa da entalpia reticular (Dm Hmº) de adutos através de termogravimetria: uso de uma equação empírica Lattice enthalpies (DMHmº) of adducts using an empirical equation supported in tg data

open access: yesQuímica Nova, 1997
An empirical equation: DMHmº = t i/b (where t i is the Kelvin temperature of the beginning of the thermal decomposition obtained from the thermogravimetry of the adducts; b is an empirical parameter wich depends on the metal halide and on the number of ...
Robson Fernandes de Farias
doaj   +1 more source

Investigation of NQO1 genetic polymorphism, NQO1 gene expression and PAH-DNA adducts in ESCC. A case-control study from Iran [PDF]

open access: yes, 2009
We evaluated the effect of NQO1 genetic variation on PAH-DNA adducts in esophageal squamous cell carcinoma (ESCC) in northeast Iran. Golestan Province in northeast of Iran has one of the highest esophageal cancer incidences in the world.
Biramijamal, F.   +4 more
core   +3 more sources

Generation of a Collision Cross Section Library for Multi-Dimensional Plant Metabolomics Using UHPLC-Trapped Ion Mobility-MS/MS

open access: yesMetabolites, 2019
The utility of metabolomics is well documented; however, its full scientific promise has not yet been realized due to multiple technical challenges. These grand challenges include accurate chemical identification of all observable metabolites and the ...
Mark Schroeder   +4 more
doaj   +1 more source

Amine catalysis for the organocatalytic diboration of challenging alkenes [PDF]

open access: yes, 2016
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The generation of in situ sp 2 –sp 3 diboron adducts has revolutionised the synthesis of organoboranes.
Althaus   +35 more
core   +1 more source

MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA [PDF]

open access: yes, 2012
Topoisomerase II creates a double-strand break intermediate with topoisomerase covalently coupled to the DNA via a 5'-phosphotyrosyl bond. These intermediate complexes can become cytotoxic protein-DNA adducts and DSB repair at these lesions requires ...
Austin, Caroline   +10 more
core   +3 more sources

Toxicity of acrylamide and its metabolite – Glicydamide

open access: yesMedycyna Pracy, 2013
Acrylamide is a synthetic chemical compound commonly used in many branches of industry. It is mainly used in the synthesis of polyacrylamides, which are widely employed in plastics, paints, varnishes, adhesives and mortars production.
Daria Pingot   +3 more
doaj   +1 more source

Correlation between levels of 2, 5-hexanedione and pyrrole adducts in tissues of rats exposure to n-hexane for 5-days. [PDF]

open access: yesPLoS ONE, 2013
The formation of pyrrole adducts might be responsible for peripheral nerve injury caused by n-hexane. The internal dose of pyrrole adducts would supply more information for the neurotoxicity of n-hexane.
Hongyin Yin   +4 more
doaj   +1 more source

Human Brain Lipidomics: Utilities of Chloride Adducts in Flow Injection Analysis

open access: yesLife, 2021
Ceramides have been implicated in a number of disease processes. However, current means of evaluation with flow infusion analysis (FIA) have been limited primarily due to poor sensitivity within our high-resolution mass spectrometry lipidomics analytical
Paul L. Wood   +6 more
doaj   +1 more source

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