Results 11 to 20 of about 230,703 (323)
Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation [PDF]
, 1997 Reductive activation of racemic 1,10-bis(acetoxy)-7-methoxymitosene WV15 in the presence of DNA, followed by enzymatic digestion and HPLC analysis, revealed the formation of various DNA adducts.
Duynhoven, John P.M. van +8 more
core +2 more sources
Toxins, 2022 Pyrrolizidine alkaloids (PAs) have been found in over 6000 plants worldwide and represent the most common hepatotoxic phytotoxins. Catalyzed by hepatic cytochrome P450 enzymes, PAs are metabolized into reactive pyrrolic metabolites, which can alkylate ...
Lin Zhu +5 more
doaj +1 more source
A Theoretical and Experimental Study on the Lewis Acid−Base Adducts (P4E3)·(BX3) (E = S, Se; X = Br, I) and (P4Se3)·(NbCl5) [PDF]
, 2001 The Lewis acid−base adducts (P4E3)·(BX3) (E = S, Se; X = Br, I) and (P4Se3)·(NbCl5) have been prepared and characterized by Raman, IR, and solid-state 31P MAS NMR spectroscopy. Hybrid density functional calculations (B3LYP) have been carried out for both
Aubauer, Christoph +5 more
core +1 more source
Química Nova, 1997 An empirical equation: DMHmº = t i/b (where t i is the Kelvin temperature of the beginning of the thermal decomposition obtained from the thermogravimetry of the adducts; b is an empirical parameter wich depends on the metal halide and on the number of ...
Robson Fernandes de Farias
doaj +1 more source
DNA adducts in fish following an oil spill exposure [PDF]
, 2006 On 12 December 1999, one third of the load of the Erika tanker, amounting to about 10,000 t crude oil flowed into sea waters close to the French Atlantic Coast.
A. Amat +36 more
core +3 more sources
Metabolites, 2019 The utility of metabolomics is well documented; however, its full scientific promise has not yet been realized due to multiple technical challenges. These grand challenges include accurate chemical identification of all observable metabolites and the ...
Mark Schroeder +4 more
doaj +1 more source
Investigation of NQO1 genetic polymorphism, NQO1 gene expression and PAH-DNA adducts in ESCC. A case-control study from Iran [PDF]
, 2009 We evaluated the effect of NQO1 genetic variation on PAH-DNA adducts in esophageal squamous cell carcinoma (ESCC) in northeast Iran. Golestan Province in northeast of Iran has one of the highest esophageal cancer incidences in the world.
Biramijamal, F. +4 more
core +3 more sources
Interactions of Cisplatin and Daunorubicin at the chromatin level [PDF]
, 2020 Unexpectedly, the widely used anticancer agents Cisplatin (Cis-Pt) and Daunorubicin (Dauno) exhibited cell type- and concentration-dependent synergy or antagonism in vitro.
Bacsó, Zsolt +7 more
core +2 more sources
Protein Adductomics: Methodologies for Untargeted Screening of Adducts to Serum Albumin and Hemoglobin in Human Blood Samples. [PDF]
, 2019 The reaction products of electrophiles in vivo can be measured as adducts to the abundant proteins, hemoglobin (Hb), and human serum albumin (HSA), in human blood samples.
Carlsson, Henrik +2 more
core +2 more sources
Toxicity of acrylamide and its metabolite – Glicydamide
Medycyna Pracy, 2013 Acrylamide is a synthetic chemical compound commonly used in many branches of industry. It is mainly used in the synthesis of polyacrylamides, which are widely employed in plastics, paints, varnishes, adhesives and mortars production.
Daria Pingot +3 more
doaj +1 more source