Correlation between levels of 2, 5-hexanedione and pyrrole adducts in tissues of rats exposure to n-hexane for 5-days. [PDF]
The formation of pyrrole adducts might be responsible for peripheral nerve injury caused by n-hexane. The internal dose of pyrrole adducts would supply more information for the neurotoxicity of n-hexane.
Hongyin Yin +4 more
doaj +1 more source
Human Brain Lipidomics: Utilities of Chloride Adducts in Flow Injection Analysis
Ceramides have been implicated in a number of disease processes. However, current means of evaluation with flow infusion analysis (FIA) have been limited primarily due to poor sensitivity within our high-resolution mass spectrometry lipidomics analytical
Paul L. Wood +6 more
doaj +1 more source
Amine catalysis for the organocatalytic diboration of challenging alkenes [PDF]
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The generation of in situ sp 2 –sp 3 diboron adducts has revolutionised the synthesis of organoboranes.
Althaus +35 more
core +1 more source
Dithiocarbamate complexes have remained prominent as single source precursors for the synthesis of clean metal sulfide nanoparticles. This study reports the synthesis of lead sulfide (PbS) nanoparticles using some novel complexes of 1, 10-phenanthroline ...
Jerry O. Adeyemi, Damian C. Onwudiwe
doaj +1 more source
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA [PDF]
Topoisomerase II creates a double-strand break intermediate with topoisomerase covalently coupled to the DNA via a 5'-phosphotyrosyl bond. These intermediate complexes can become cytotoxic protein-DNA adducts and DSB repair at these lesions requires ...
Austin, Caroline +10 more
core +3 more sources
An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]
Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan +16 more
core +3 more sources
Synthesis and characterization of manganese-glycine and copper-glycine adducts
This work reports the synthesis and characterization of adducts of general formula MCl2.ngly, where M= Mn and Cu; n= 2 and 4, and gly= glycine. The manganese adducts were synthesized by dissolution of both, manganese chloride and glycine in water ...
Robson Fernandes de Farias
doaj +1 more source
Biological exposure indices of pyrrole adducts in serum and urine for hazard assessment of n-hexane exposure. [PDF]
BACKGROUND: Pyrrole adducts might be used as a biomarker for monitoring occupational exposure to n-hexane, but the Biological Exposure Indices of pyrrole adducts in serum and urine are still unknown.
Hongyin Yin +6 more
doaj +1 more source
Resonance Raman Spectroscopy Reveals that Substrate Structure Selectively Impacts the Heme-Bound Diatomic Ligands of CYP17 [PDF]
An important function of steroidogenic cytochromes P450 is the transformation of cholesterol to produce androgens, estrogens, and the corticosteroids.
Gregory, Michael C. +3 more
core +2 more sources
Factors Influencing the Formation of Chemical–Hemoglobin Adducts
Hemoglobin (Hb) adducts have been used as biomarkers for the internal exposure to chemicals. Simultaneous exposure to chemicals that bond with the N-terminal valine of Hb to form adducts, such as glycidol, acrylamide, and glucose, may affect the ...
Yuko Shimamura +6 more
doaj +1 more source

