Results 251 to 260 of about 772,486 (361)

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools.

, 1989
Eliezer Rapaport, J. Fontaine
openalex   +2 more sources

The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosis

Cell Death and Differentiation, 2009
W. Malorni, M. G. Farrace, P. Matarrese, A. Tinari, L. Ciarlo, P. Mousavi-Shafaei, M. D’Eletto, G. D. Giacomo, G. Melino, L. Palmieri, C. Rodolfo, M. Piacentini   +11 more
semanticscholar   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Adenine nucleotide translocation in spinach chloroplasts [PDF]

FEBS Letters, 1969
openaire   +3 more sources

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

Biological Reviews, EarlyView.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto, Jana Asselman, Patrícia Pereira, Joana Luísa Pereira   +3 more
wiley   +1 more source

Targeting Wnt/β‐Catenin Pathway by DNA Alkylating Pyrrole‐Imidazole Polyamide in Colon Cancer

Cancer Science, EarlyView.
Wnt/β‐catenin pathway is aberrantly activated in various cancers. We have synthesized a novel DNA alkylating PI polyamide (WNT‐Chb) to target the consensus TCF/LEF‐responsible element. WNT‐Chb downregulated the Wnt‐target genes by inhibiting the recruitment of the β‐catenin/TCF transcription complex and reduced tumor growth in a mouse xenograft tumor ...
Osamu Shimozato, Natsue Akao, Yoko Yanagisawa, Yusuke Mori, Xudong Zhang, Yuki Kida, Rie Igarashi, Takayoshi Watanabe, Toshinori Ozaki, Atsushi Takatori   +9 more
wiley   +1 more source

Effects of hypobaric hypoxia on adenine nucleotide pools, adenine nucleotide transporter activity and protein expression in rat liver

, 2006
Congyang Li
openalex   +2 more sources

Cardioprotection and altered mitochondrial adenine nucleotide transport

Basic Research in Cardiology, 2009
C. Steenbergen, Samarjit Das, Jason Su, Renee P. Wong, E. Murphy   +4 more
semanticscholar   +1 more source

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source