Results 251 to 260 of about 177,004 (319)

Adenine nucleotide degradation during energy depletion in human lymphoblasts. Adenosine accumulation and adenylate energy charge correlation.

, 1979
SS Matsumoto, Kari O. Raivio, J. Edwin Seegmiller   +2 more
openalex   +1 more source

L‐Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU‐08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway

Aging Cell, EarlyView.
Bifidobacterium pseudocatenulatum NCU‐08, isolated from the feces of centenarians, facilitated the entry of L‐tryptophan into hippocampal neurons of SAMP8 mice, where it was metabolized into NAD+. The increased NAD+ levels activated Sirt1 protein, thereby suppressing the expression of senescence‐associated proteins P53, P21, and Rb, ultimately delaying
Tangchang Xu, Xiaoyun Wu, Yifei Zhang, Yujie Cai, Xinfeng Zhang, Qingwei Zeng, Jie Luo, Jing Wei, Tingtao Chen   +8 more
wiley   +1 more source

Control of complex metal ion equilibria in biochemical reaction systems. Intrinsic and apparent stability constants of metal-adenine nucleotide complexes.

, 1978
Robert Adolfsen, Evangelos N. Moudrianakis   +1 more
openalex   +1 more source

The Human Cardiac “Age‐OME”: Age‐Specific Changes in Myocardial Molecular Expression

Aging Cell, EarlyView.
A multi‐omics analysis was performed to uncover the molecular landscape of human cardiac ageing. We report several insights for the first time: a decrease in proteins composing the structural machinery of the heart; a likely compensatory increase in energetic flux and redox reductive capacity; and an increase in lysosomal activity.
Cassandra Malecki, Giovanni Guglielmi, Benjamin Hunter, Dylan Harney, Yen Chin Koay, Anthony. S. Don, Oscar Han, Jasmine Khor, Lisa Nguyen, Michael Pan, Peter Gawthrop, Nathan Isles, Joshua Chung, Robert. D. Hume, Matthew Taper, XiaoSuo Wang, Mark Larance, Fabian Spill, Vijay Rajagopal, John F. O’Sullivan, Sean Lal   +20 more
wiley   +1 more source

Editorial: Adenine nucleotides in immunity and inflammation

Frontiers in Immunology
Christa E. Müller, Santina Bruzzone, Andreas H. Guse   +2 more
openaire   +3 more sources

Reproductive functions and fertility preservation in men with sickle cell disease

Andrology, EarlyView.
Abstract Background Sickle cell disease (SCD) is a prevalent hereditary disorder with significant morbidity, including potential impacts on male fertility. This study aims to evaluate the semen parameters in men with SCD and assess the outcomes of fertility preservation strategies.
Clarisse Leblanc, Nathalie Sermondade, Diane Rivet‐Danon, Ludmilla Aworet‐Ogouma, Anna Ly, Guillaume Bachelot, Françoise Lionnet, Aline Santin, Anne‐Gael Cordier, Kamila Kolanska, Rachel Lévy, Isabelle Berthaut, Charlotte Dupont   +12 more
wiley   +1 more source

The Role of Adenine Nucleotide Translocase in the Assembly of Respiratory Supercomplexes in Cardiac Cells. [PDF]

Cells, 2019
M Parodi-Rullán R, Chapa-Dubocq X, Guzmán-Hernández R, Jang S, A Torres-Ramos C, Ayala-Peña S, Javadov S.   +6 more
europepmc   +1 more source

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

British Journal of Pharmacology, EarlyView.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau, Awa Isma Ba, Audrey Geissler, Romain Barbosa, Abhishek Basu, Arif Muhammad, Marina Nivot, Maéva Loriot, Julia Leemput, Patricia Passilly‐Degrace, Sébastien Causse, Laurent Demizieux, Hélène François, Bruno Vergès, Jianmin Duan, Geneviève Gaucher, Michael Harvey, Pascal Degrace, Glenn Crater, Resat Cinar, Tony Jourdan   +20 more
wiley   +1 more source

Tentoxin-induced energy-independent adenine nucleotide exchange and ATPase activity with chloroplast coupling factor 1.

, 1978
S. Reimer, Bruce R. Selman
openalex   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source