Results 1 to 10 of about 667,037 (306)

Design and Characterization of Elastic Artificial Skin Containing Adenosine-Loaded Solid Lipid Nanoparticles for Treating Wrinkles

Pharmaceutics, 2020
Adenosine (AD), which is used for treating wrinkles, exhibits poor skin permeation. The aim of the present study was to develop a cross-linked silicone-based cellulose elastomer as an elastic artificial skin for the treatment of skin wrinkles, a ...
Sooho Yeo, Sukkyun Jung, Heui Kyoung Cho, Young Ho Kim, Gi Hwan Kim, Dohyun Kim, Byoung Hyen Ko, Jaehwi Lee   +7 more
doaj   +1 more source

New insights into the biological role of mammalian ADARs; the RNA editing proteins [PDF]

, 2015
The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA.
Arieti, Fabiana, Gallo, Angela, Keegan, Liam P., Mannion, Niamh, O'Connell, Mary A.   +4 more
core   +2 more sources

Increased Number of Circulating CD8/CD26 T Cells in the Blood of Duchenne Muscular Dystrophy Patients Is Associated with Augmented Binding of Adenosine Deaminase and Higher Muscular Strength Scores

Frontiers in Pharmacology, 2017
Duchenne muscular dystrophy (DMD) is an X-linked disorder that leads to cardiac and skeletal myopathy. The complex immune activation in boys with DMD is incompletely understood.
Jonathan H. Soslow, Larry W. Markham, Larry W. Markham, W. Bryan Burnette, Cristi L. Galindo, Igor Feoktistov, Frank J. Raucci, Bruce M. Damon, Douglas B. Sawyer, Douglas B. Sawyer, Sergey Ryzhov   +10 more
doaj   +1 more source

Decreased Equilibrative Nucleoside Transporter 1 (ENT1) Activity Contributes to the High Extracellular Adenosine Levels in Mesenchymal Glioblastoma Stem-Like Cells

Cells, 2020
Glioblastoma multiforme is one of the most malignant types of cancer. This is mainly due to a cell subpopulation with an extremely aggressive potential, called glioblastoma stem-like cells (GSCs).
Sebastián Alarcón, María de los Ángeles Toro, Carolina Villarreal, Rómulo Melo, Rodrigo Fernández, Angel Ayuso Sacido, Daniel Uribe, Rody San Martín, Claudia Quezada   +8 more
doaj   +1 more source

Ammonia : this is not the end but rather the end of the beginning [PDF]

, 2018
Hepatic encephalopathy (HE) represents a wide spectrum of neurological or neuropsychological symptoms caused by liver disease and/or portosystemic shunts.
Dam, Gitte, Rose, Christopher, Weiss, Nicolas   +2 more
core   +1 more source

Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex

Frontiers in Pharmacology, 2018
Caffeine is the most widely used psychoactive drug, bolstering attention and normalizing mood and cognition, all functions involving cerebral cortical circuits.
Amber Kerkhofs, Amber Kerkhofs, Ana C. Xavier, Beatriz S. da Silva, Paula M. Canas, Sander Idema, Johannes C. Baayen, Samira G. Ferreira, Rodrigo A. Cunha, Rodrigo A. Cunha, Huibert D. Mansvelder   +10 more
doaj   +1 more source

Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve [PDF]

, 2017
Background—Contrast fractional flow reserve (cFFR) is a method for assessing functional significance of coronary stenoses, which is more accurate than resting indices and does not require adenosine.
Berry, Colin, Choi, Dong-Hyun, De Bruyne, Bernard, Fearon, William F., Gould, K. Lance, Jeremias, Allen, Johnson, Nils P., Kobayashi, Yuhei, Nishi, Takeshi, Oldroyd, Keith G., Pijls, Nico H.J.   +10 more
core   +1 more source

The role of the neuromodulator adenosine in alcohols actions. [PDF]

, 1997
The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core  

Caffeine. cognitive and physical performance enhancer or psychoactive drug? [PDF]

, 2015
Caffeine use is increasing worldwide. The underlying motivations are mainly concentration and memory enhancement and physical performance improvement. Coffee and caffeine-containing products affect the cardiovascular system, with their positive inotropic
Aromatario, Mariarosaria, Cappelletti, Simone, Piacentino, Daria, Sani, Gabriele   +3 more
core   +1 more source

Cytokine-Induced Killer Cells Express CD39, CD38, CD203a, CD73 Ectoenzymes and P1 Adenosinergic Receptors

Frontiers in Pharmacology, 2018
Cytokine-induced killer (CIK) cells, a heterogeneous T cell population obtained by in vitro differentiation of peripheral blood mononuclear cells (PBMC), represent a promising immunological approach in cancer.
Alberto L. Horenstein, Antonella Chillemi, Roberta Zini, Valeria Quarona, Nicoletta Bianchi, Rossella Manfredini, Roberto Gambari, Fabio Malavasi, Davide Ferrari   +8 more
doaj   +1 more source