Results 1 to 10 of about 970,574 (224)

Optical ATP biosensor for extracellular ATP measurement [PDF]

open access: yesBiosensors and Bioelectronics, 2013
Extracellular Adenosine-5'-triphosphate (ATP) is an important multi-functional molecule which can mediate numerous physiological activities by activating purinergic P2 receptors. The objective of this study was to develop a novel optical ATP sensor for in-situ extracellular ATP measurement in biological tissues.
C, Wang, C-Y C, Huang, W-C, Lin
exaly   +3 more sources

IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3

open access: yesBiomedicines, 2022
Although the effects of growth hormone (GH) therapy on spinocerebellar ataxia type 3 (SCA3) have been examined in transgenic SCA3 mice, it still poses a nonnegligible risk of cancer when used for a long term. This study investigated the efficacy of IGF-1,
Yong-Shiou Lin   +5 more
doaj   +1 more source

Impact of sorbitol and l-carnitine on stimulating thyroid hormone, triiodothyronine and adenosine triphosphate level in broilers [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
In order to provide more significant physiological benefits for the poultry sector, our research sought to assess the effectiveness of the two metabolic products, Sorbitol and L-carnitine, for energy production.
Hiyam N. Maty
doaj   +1 more source

A pilot study: handgrip as a predictor in the disease progression of SCA3

open access: yesOrphanet Journal of Rare Diseases, 2023
Background Spinocerebellar ataxia type 3 (SCA3) is an inherited, autosomal, and rare neurodegenerative disease. Serum/plasma biomarkers or functional magnetic resonance imaging used to assess progression, except for neurological examinations, is either ...
Chungmin Chiu   +8 more
doaj   +1 more source

Making ATP [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
We present a mesoscopic model for ATP synthesis by F 1 F o ATPase. The model combines the existing experimental knowledge of the F 1 enzyme into a consistent mathematical model that illuminates how the stages in ...
Jianhua, Xing   +2 more
openaire   +2 more sources

Association of leukocyte mitochondrial DNA copy number with longitudinal C-reactive protein levels and survival in older adults: a cohort study

open access: yesImmunity & Ageing, 2022
Background Systemic chronic inflammation occurs with age. The association of the leukocyte mitochondrial DNA copy number, a measure of mitochondrial function in aging, with the temporal profile of serum high-sensitivity C-reactive protein and mortality ...
I-Chien Wu   +9 more
doaj   +1 more source

Targeting the Key Enzymes of Abnormal Fatty Acid β-oxidation as a Potential Strategy for Tumor Therapy

open access: yesFrontiers in Bioscience-Landmark, 2022
Fatty acid metabolism has attracted extensive attention for its key role in the occurrence and development of tumors. Fatty acids not only participate in the biosynthesis of phospholipids in the membrane to overcome the demand for rapidly proliferating ...
Hongdan Chen   +5 more
doaj   +1 more source

To ATP or Not To ATP: This Is the Question [PDF]

open access: yesThe Journal of General Physiology, 2008
Volume 131, No. 2, February 4, 2008. Pages [105–108][1]. The original version of this commentary contained citation errors. Citations of Bennetts et al., 2001, should have been Bennetts et al., 2007, with the exception of page 106, right column, line 30.
openaire   +3 more sources

ATP‐induced ATP release from astrocytes [PDF]

open access: yesJournal of Neurochemistry, 2003
AbstractPropagation of interastrocyte Ca2+waves is mediated by diffusion of extracellular adenosine triphosphate (ATP), and may require regenerative release of ATP. The ability of ATP to initiate release of intracellular ATP was assessed by labeling adenine nucleotide pools in astrocyte cultures with14C‐adenine.
Christopher M, Anderson   +2 more
openaire   +2 more sources

Closing a Key Gap in DSCSA Compliance with Credentialing

open access: yesBlockchain in Healthcare Today, 2023
In this session, the Open Credentialing Initiative (OCI) introduces the concept and practical application of electronic credentials. The audience will learn about their use in the context of DSCSA and how they enable timely compliance with the DSCSA ...
Bob Celeste, David Kessler
doaj   +1 more source

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