Results 21 to 30 of about 963,526 (173)

ATP-dependent DNA supercoiling assay.

, 2016
Supercoiling activities of DNA gyrases composed of WT-GyrA, Gly89Cys-GyrA, Ala91Val-GyrA or Asp95Gly-GyrA and WT-GyrB were confirmed. Relaxed pBR322 DNA was incubated with GyrA, GyrB, or both, of the subunits in the presence or absence of ATP.
Kazumasa Yokoyama (127298), Chie Nakajima (127312), Tomoyuki Yamaguchi (150399), Yasuhiko Suzuki (378)   +3 more
core   +1 more source

Outcome of ATP-based tumor chemosensitivity assay directed chemotherapy in heavily pre-treated recurrent ovarian carcinoma [PDF]

, 2003
BACKGROUND: We wished to evaluate the clinical response following ATP-Tumor Chemosensitivity Assay (ATP-TCA) directed salvage chemotherapy in a series of UK patients with advanced ovarian cancer. The results are compared with that of a similar assay used
Pauline A Whitehouse, Federica Di Nicolantonio, Whitehouse, PA, Cree, IA, Bernard R Higgins, Di Nicolantonio Federica, Mercer Stuart J, Cree Ian A, Knight, LA, Higgins, BR, Osborne Richard, Kurbacher, CM, Kurbacher Christian M, Di Nicolantonio, Federica, Stuart J Mercer, Osborne, R, Richard Osborne, Alan Lamont, Whitehouse Pauline A, Louise A Knight, Sanjay Sharma, Di Nicolantonio, F, Neale Michael H, Andrew C Hindley, Hindley Andrew C, Sharma Sanjay, Knight Louise A, Lamont, A, Higgins Bernard R, Neale, MH, Ian A Cree, Hindley, AC, Mercer, SJ, Lamont Alan, Michael H Neale, Christian M Kurbacher, Sharma, S   +36 more
core   +2 more sources

Nutrient‐specific combinatorial secretion of GLP‐1 and neurotransmitters in the enteroendocrine L‐cell line GLUTag

The FEBS Journal, EarlyView.
Enteroendocrine L cells function as chemosensors in the intestine. Using the L‐cell line GLUTag, we show that distinct nutrients trigger different combinations of co‐secretion of GLP‐1 and neurotransmitters: D‐glucose evokes GLP‐1, glutamate, and ATP; L‐glutamine evokes GLP‐1 and glutamate; sucralose and butyrate evoke only GLP‐1.
Yo Ito, Kazuki Harada, Yuri Osuga‐Yoshiike, Masami Yokota Hirai, Tetsuya Kitaguchi, Takashi Tsuboi   +5 more
wiley   +1 more source

ATP-Driven Temporal Control over Structure Switching of Polymeric Micelles

, 2018
An adenosine triphosphate (ATP)-fueled micellar system in the out-of-equilibrium state was constructed based on 4,5-diamino-1,3,5-triazine (DAT)-containing block copolymer.
Cong Hu, Li Liu, Li Liu (75607), Cong Hu (824712), Bingyang Dong, Bingyang Dong (5635769)   +5 more
core   +1 more source

Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes [PDF]

, 2013
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa
Peppiatt-Wildman, C. M., C. M. Peppiatt-Wildman, Scott S Wildman, C. Crawford, Wildman, Scott S.P., Kennedy-Lydon, T. M., M. C. Kelly, Wildman, S. S. P., Peppiatt-Wildman, Claire M., S. S. P. Wildman, T. M. Kennedy-Lydon, Kelly, M. C., Crawford, C.   +12 more
core   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Mapping the interactions between ATP and the sarcoplasmic reticulum Ca 2 + -ATPase with ATP and ATP analogs studied by Fourier transform infrared spectroscopy [PDF]

, 2004
Die Infrarotspektroskopie in Verbindung mit photoaktivierbaren Substraten wurde zur Untersuchung von Substrat-Protein-Wechselwirkungen eingesetzt. Dabei wurden Konformationsänderungen der Ca2+-ATPase des Sarkoplasmatischen Retikulums bei Bindung des ...
Liu, Man
core  

ATP-LipidsProtein Anchor and Energy Source in Two Dimensions^⊥

, 2016
The ubiquitous function of ATP as energy equivalent in nature has resulted in a common folding pattern of ATP-binding proteins. Their binding pocket tolerates modifications of the adenine ring to some extend, whereas those of the triphosphate group ...
Robert Tampé (377578), Lutz Schmitt (219319)   +1 more
core   +2 more sources

Fluorescence Sensing of Anions Like Adenosine 5ʹ‐Triphosphate With pH‐Gated Porous Dye‐Loaded Cerasomes

Small, Volume 22, Issue 61, 2 November 2026.
The development of gated systems enabling controlled pore opening offers new opportunities for sensing applications. This study explores dye loading in porous and non‐porous cerasomes and pH‐dependent ATP‐triggered gating via polyamine anchors. Porous cerasomes were synthesized using block‐co‐polymers, enabling controlled proton influx and fluorescence‐
Romane Vinot, Estela Climent, Maja Friedrich, Jérémy Bell, Knut Rurack   +4 more
wiley   +1 more source

P2X₃ Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP [PDF]

, 2001
The present study explores the possible involvement of a purinergic mechanism in mechanosensory transduction in the bladder using P2X₃ receptor knock-out (P2X₃ ⁻⁄⁻) and wild-type control (P2X₃ ⁺⁄⁺) mice.
Bodin, P, Cockayne, DA, Kasakov, L, Burnstock, G, Rong, W, Bardini, M, Ford, APDW, Vlaskovska, M   +7 more
core