Results 1 to 10 of about 5,208 (113)
Frontiers in Microbiology, 2021 The vacuole of Candida albicans plays a significant role in many processes including homeostasis control, cellular trafficking, dimorphic switching, and stress tolerance.
Quanzhen Lv, Lan Yan, Yuanying Jiang
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Evolutionary primacy of sodium bioenergetics
Biology Direct, 2008 Background The F- and V-type ATPases are rotary molecular machines that couple translocation of protons or sodium ions across the membrane to the synthesis or hydrolysis of ATP.
Wolf Yuri I +4 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
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Cell Reports, 2017 Vacuolar H+-ATPase (v-ATPase) is a multi-subunit complex comprising two domains: the cytosolic V1 domain catalyzing ATP hydrolysis and the membranous V0 sector translocating protons across membranes.
Anna Bodzęta +2 more
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Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states
eLife, 2016 A molecular model that provides a framework for interpreting the wealth of functional information obtained on the E. coli F-ATP synthase has been generated using cryo-electron microscopy.
Meghna Sobti +6 more
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Expression and role of ATP synthase α-subunit in gemcitabine-resistant bladder cancer cells [PDF]
精准医学杂志Objective To investigate the expression and potential role of ATP synthase α-subunit (ATP5A1) in gemci-tabine-resistant bladder cancer cells. Methods Human bladder transitional cell carcinoma cell lines T24 and 5637 were used to establish gemcitabine ...
MI Zhiyuan, LIANG Ye, NIU Haitao
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Cryo-EM studies of the rotary H+-ATPase/synthase from Thermus thermophilus
Biophysics and Physicobiology, 2019 Proton-translocating rotary ATPases couple proton influx across the membrane domain and ATP hydrolysis/synthesis in the soluble domain through rotation of the central rotor axis against the surrounding peripheral stator apparatus.
Atsuko Nakanishi +3 more
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Effect of antihypertensive agents - captopril and nifedipine - on the functional properties of rat heart mitochondria [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): Investigation of acute effect on cellular bioenergetics provides the opportunity to characterize the possible adverse effects of drugs more comprehensively.
Ivana Kancirová +5 more
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Advanced Healthcare Materials, EarlyView.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
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Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
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