Results 11 to 20 of about 420,897 (152)

Evolutionary primacy of sodium bioenergetics [PDF]

Biology Direct, 2008
Background The F- and V-type ATPases are rotary molecular machines that couple translocation of protons or sodium ions across the membrane to the synthesis or hydrolysis of ATP.
Koonin Eugene V, Mulkidjanian Armen Y, Armen Y Mulkidjanian, Kira S Makarova, Makarova Kira S, Michael Y Galperin, Yuri I Wolf, Galperin Michael Y, Wolf Yuri I, Eugene V Koonin   +9 more
core   +3 more sources

Beyond Bioenergetics: Moonlighting Functions of F₁F_O-ATPase From ATP Synthesis to an ATP-Wasting Death Switch. [PDF]

Med Res Rev
ABSTRACT Mitochondrial F1FO‐ATPase is classically viewed as the “splendid” rotary nanomachine that sustains life by converting the proton‐motive force (pmf) into ATP. Yet this same complex can adopt a second, context‐dependent function that links bioenergetics to cell fate.
Nesci S.
europepmc   +2 more sources

The Importance of Vacuolar Ion Homeostasis and Trafficking in Hyphal Development and Virulence in Candida albicans

Frontiers in Microbiology, 2021
The vacuole of Candida albicans plays a significant role in many processes including homeostasis control, cellular trafficking, dimorphic switching, and stress tolerance.
Quanzhen Lv, Lan Yan, Yuanying Jiang
doaj   +1 more source

Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex [PDF]

, 2004
Kluge C, Seidel T, Bolte S, et al. Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex. BMC Cell Biology. 2004;5(1):29.Background: Vacuolar H+-ATPases are large protein
Thorsten Seidel, Bolte Susanne, Kluge Christoph, Sauer, Markus, Hanitzsch, M, Kluge, C, Shanti S Sharma, Hanitzsch Miriam, Markus Sauer, Karl-Josef Dietz, Ross, J, Dortje Golldack, Satiat-Jeunemaitre Beatrice, Sharma, S. S., Golldack, Dortje, Christoph Kluge, Joachim Roß, Satiat-Jeunemaitre, B, Sharma Shanti S, Golldack Dortje, Dietz Karl-Josef, Susanne Bolte, Dietz, Karl-Josef, Bolte, S, Seidel Thorsten, Sauer Markus, Miriam Hanitzsch, Seidel, Thorsten, Beatrice Satiat-Jeunemaitre, Roß Joachim, Ross, Joachim, Bolte, Susanne, Kluge, Christoph, Satiat-Jeunemaitre, Beatrice, Sharma, Shanti S, Hanitzsch, Miriam   +35 more
core   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery

Cell Reports, 2017
Vacuolar H+-ATPase (v-ATPase) is a multi-subunit complex comprising two domains: the cytosolic V1 domain catalyzing ATP hydrolysis and the membranous V0 sector translocating protons across membranes.
Anna Bodzęta, Martin Kahms, Jürgen Klingauf   +2 more
doaj   +1 more source

Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states

eLife, 2016
A molecular model that provides a framework for interpreting the wealth of functional information obtained on the E. coli F-ATP synthase has been generated using cryo-electron microscopy.
Meghna Sobti, Callum Smits, Andrew SW Wong, Robert Ishmukhametov, Daniela Stock, Sara Sandin, Alastair G Stewart   +6 more
doaj   +1 more source

Structural comparison of the vacuolar and Golgi V-ATPases from Saccharomyces cerevisiae [PDF]

, 2019
Proton-translocating vacuolar-type ATPases (V-ATPases) are necessary for numerous processes in eukaryotic cells, including receptor-mediated endocytosis, protein maturation, and lysosomal acidification.

core   +1 more source

Expression and role of ATP synthase α-subunit in gemcitabine-resistant bladder cancer cells [PDF]

精准医学杂志
Objective To investigate the expression and potential role of ATP synthase α-subunit (ATP5A1) in gemci-tabine-resistant bladder cancer cells. Methods Human bladder transitional cell carcinoma cell lines T24 and 5637 were used to establish gemcitabine ...
MI Zhiyuan, LIANG Ye, NIU Haitao
doaj   +1 more source

Impact of an electric field on P-type ATPases [PDF]

, 2008
P-type ATPases are membrane proteins acting as ion pumps that drive an active transport of cations across the membrane against a concentration gradient. The required energy for the ion transport is provided by binding and hydrolysis of ATP.
Weidemüller, Christian, Hauser, Karin
core   +1 more source