Results 21 to 30 of about 420,897 (152)

Cryo-EM studies of the rotary H+-ATPase/synthase from Thermus thermophilus

Biophysics and Physicobiology, 2019
Proton-translocating rotary ATPases couple proton influx across the membrane domain and ATP hydrolysis/synthesis in the soluble domain through rotation of the central rotor axis against the surrounding peripheral stator apparatus.
Atsuko Nakanishi, Jun-ichi Kishikawa, Kaoru Mitsuoka, Ken Yokoyama   +3 more
doaj   +1 more source

Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis [PDF]

, 2008
Seidel T, Schnitzer D, Golldack D, Sauer M, Dietz K-J. Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis. BMC Cell Biology. 2008;9(1): 28.BACKGROUND: The V-ATPase (VHA) is a protein complex of 13 different VHA-subunits.
Thorsten Seidel, Sauer, Markus, Golldack Dortje, Dietz Karl-Josef, Markus Sauer, Karl-Josef Dietz, Daniel Schnitzer, Dietz, Karl-Josef, Dortje Golldack, Schnitzer Daniel, Seidel Thorsten, Sauer Markus, Golldack, Dortje, Seidel, Thorsten, Schnitzer, Daniel   +14 more
core   +1 more source

Archazolid and apicularen: novel specific V-ATPase inhibitors. [PDF]

, 2005
V-ATPases constitute a ubiquitous family of heteromultimeric, proton translocating proteins. According to their localization in a multitude of eukaryotic membranes, they energize many different transport processes.
Brigitte Kunze, Jansen, Rolf, Steinmetz, Heinrich, Wieczorek, Helmut, Rolf Jansen, Florenz Sasse, Huss, Markus, Ingenhorst, Gudrun, Heinrich Steinmetz, Kunze, Brigitte, Helmut Wieczorek, Axel Zeeck, Markus Huss, Zeeck, Axel, Sasse, Florenz, Gudrun Ingenhorst   +15 more
core   +1 more source

Effect of antihypertensive agents - captopril and nifedipine - on the functional properties of rat heart mitochondria [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): Investigation of acute effect on cellular bioenergetics provides the opportunity to characterize the possible adverse effects of drugs more comprehensively.
Ivana Kancirová, Magdaléna Jašová, Iveta Waczulíková, Táňa Ravingerová, Attila Ziegelhöffer, Miroslav Ferko   +5 more
doaj  

Evolutionary links between FliH/YscL-like proteins from bacterial type III secretion systems and second-stalk components of the FoF1 and vacuolar ATPases

, 2006
Bacterial type III secretion drives flagellar biosynthesis and mediates bacterial-eukaryotic interactions. Type III secretion is driven by an ATPase that is homologous to the catalytic subunits of proton-translocating ATPases, such as the FoF1 ATPase ...
Scott A. Beatson, Bailey, Christopher M, Pallen, Mark J, Beatson, Scott A, Pallen, M. J., Christopher M. Bailey, Bailey, C. M., Beatson, S. A., Mark J. Pallen   +8 more
core   +1 more source

Investigating the proton-transolcating subunit of the rotary A-type ATPase [PDF]

, 2016
All forms of life are dependent on proton gradients as a source of energy to power essential cellular processes, and they all store this energy in the form of the nucleotide adenosine triphosphate (ATP).
Laming, Elise
core   +1 more source

Membrane-associated and Solubilized ATPases of Streptococcus mutans and Streptococcus sanguis

, 1987
The proton-translocating, membrane ATPases of oral streptococci have been implicated in cytoplasmic pH regulation, acidurance, and cariogenicity. Membranes were isolated from Streptococcus mutans GS-5 and Streptococcus sanguis NCTC 10904 following salt ...
S.V.W. Sutton, R.E. Marquis
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Proton-translocating ATPase from bovine kidney medulla: partial purification and reconstitution

, 1988
The proton-translocating ATPase that is responsible both for urinary and vacuolar acidification was partially purified from bovine kidney medulla microsomes.
S. Gluck, J. Caldwell
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source