Results 41 to 50 of about 963,526 (173)

ATP modulates holdase activity of fungal and human 110‐kilodalton heat shock proteins to promote protein folding

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Heat shock proteins of the 70‐kDa family (Hsp70s) are highly abundant and conserved molecular chaperones that help preserve proteostasis primarily by facilitating proper protein folding. Heat shock protein of the 110‐kDa family (Hsp110s), a specialized branch of the Hsp70/Hsp110 superfamily, function both as nucleotide exchange factor (NEF ...
Justin M. Kidd, Cancan Sun, Alissa Garay, Mitchell Keplinger, Colin Richter, Aaron E. May, Qinglian Liu   +6 more
wiley   +1 more source

P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes [PDF]

, 2008
ATP plays an important role in signal transduction between neuronal and glial circuits and within glial networks. Here we describe currents activated by ATP in astrocytes acutely isolated from cortical brain slices by non-enzymatic mechanical ...
Lalo, Ulyana, Pankratov, Yuriy, Verkhratsky, A. N. (Alekseĭ Nestorovich), Wichert, S., Kirchhoff, F., Rossner, Moritz J., Verkhratsky, Alexei; id_orcid, Kirchhoff, Frank, Verkhratsky, Alexei, Pankratov, Y., Rossner, M., Lalo, U., Verkhratskiĭ, A. N. (Alekseĭ Nestorovich), North, R., Pankratov, Yuri, North, R. Alan, Verkhratsky, A., Wichert, Sven P.   +17 more
core   +1 more source

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2826-2842, May 2026.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu, Zhifu Xing, Jiao Li, Tangbing Yang, Huan Wu, Qiangsheng Ge, Yanju Wang, Baoan Song, Runjiang Song   +8 more
wiley   +1 more source

Mechanistic insights into ATP hydrolysis by the ABC transporter TAP [PDF]

, 2004
The transporter associated with antigen processing (TAP) plays a pivotal role in the adaptive immune response against virus-infected or malignantly transformed cells.
Chen, Min
core  

External validation of the Ramathibodi paroxysmal supraventricular tachycardia recurrence score and development of a refined prediction model in a Hong Kong emergency department adult cohort: A retrospective study

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 2, April 2026.
Abstract Background Paroxysmal supraventricular tachycardia (PSVT) recurrence after adenosine treatment is common in emergency departments (EDs), but predictive tools require validation. Objectives To externally validate the Ramathibodi PSVT recurrence score in a Hong Kong ED cohort and develop a refined local model for predicting 24‐h recurrence ...
Man Yu Chan
wiley   +1 more source

Deficient Cardiolipin Remodelling Alters Muscle Fibre Composition and Neuromuscular Connectivity in Barth Syndrome

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Barth syndrome (BTHS) is a rare X‐linked mitochondrial disorder caused by mutations in the TAFAZZIN gene, which disrupts cardiolipin (CL) remodelling and mitochondrial function. While cardiac manifestations of BTHS are well characterized in male patients, the mechanisms underlying skeletal muscle weakness and fatigability are poorly
Catalina Matias, Paige L. Snider, Elizabeth A. Sierra Potchanant, Joshua R. Huot, Rahul Raghav, Michael T. Chin, Simon J. Conway, Jeffrey J. Brault   +7 more
wiley   +1 more source

Genome‐wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

mLife, Volume 5, Issue 2, Page 180-198, April 2026.
Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei, Yawen Cai, Jianfeng Huang, Kedong Zhao, Zuqin Zhang, Dandan Yu, Shiyan Lu, Zeying Lai, Thomas K. Wood, Xinmiao Fu   +9 more
wiley   +1 more source

Purinergic ATP‐P2X7 Signaling Drives Colonic Giant Migrating Contraction in Suncus murinus

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Using Suncus murinus, this study reveals that ATP regulates colonic giant migrating contractions (GMCs). ATP activates P2X7 receptors on cholinergic neurons, triggering powerful contractions that facilitate defecation. This effect is suppressed by P2X7 receptor antagonists and atropine, identifying the ATP‐P2X7‐acetylcholine axis as a key regulatory ...
Ayano Gomi, Hozuki Shimosawa, Ichiro Sakata   +2 more
wiley   +1 more source

Import of ADP/ATP carrier into mitochondria [PDF]

, 1990
We have identified the yeast homologue of Neurospora crassa MOM72, the mitochondrial import receptor for the ADP/ATP carrier (AAC), by functional studies and by cDNA sequencing.
Dietmeier, Klaus A., Söllner, Thomas, Pfaller, Rupert, Tropschug, Maximilian, Pfanner, Nikolaus, Steger, Heinrich F., Kiebler, Michael, Neupert, Walter, Trülzsch, Konrad S.   +8 more
core   +1 more source

Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells

Chemistry – A European Journal, Volume 32, Issue 11, 16 March 2026.
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu, Kunihiko Morihiro, Rui Cong, Samruddhi Maheshwar Patil, Idoia Wille, Akimitsu Okamoto   +5 more
wiley   +1 more source