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Extracellular ATP and Neurodegeneration
ATP is a potent signaling molecule abundantly present in the CNS. It elicits a wide array of physiological effects and is regarded as the phylogenetically most ancient epigenetic factor playing crucial biological roles in several different tissues. These can range from neurotransmission, smooth muscle contraction, chemosensory signaling, secretion and ...
Volonté, Cinzia +5 more
openaire +3 more sources
The development of gated systems enabling controlled pore opening offers new opportunities for sensing applications. This study explores dye loading in porous and non‐porous cerasomes and pH‐dependent ATP‐triggered gating via polyamine anchors. Porous cerasomes were synthesized using block‐co‐polymers, enabling controlled proton influx and fluorescence‐
Romane Vinot +4 more
wiley +1 more source
The Editorial Board of Comparative Politics Russia publishes the second part of the situational analysis which was held in the form of a roundtable to share the results of the analysis of the dynamics and current state of the development of Russian ...
article editorial
doaj +1 more source
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
Mutations to the histone H3 alpha N region selectively alter the outcome of ATP-dependent nucleosome-remodelling reactions [PDF]
Mutational analysis of the histone H3 N-terminal region has shown it to play an important role both in chromatin function in vivo and nucleosome dynamics in vitro.
Owen-Hughes, Tom; id_orcid +1 more
core +1 more source
Regulation of metabolic pathways PVY-RNA biosynthesis in tobacco: glycolytic pathway
Tobacco plants infected with potato virus Y were studied at the stage of acute infection. Key enzymes of the glycolytic pathway, their regulation and the content of involved intermediates were monitored.
Luděk Šindelář +1 more
doaj +1 more source
Simulated microgravity (SMG) induces host‐cell‐specific mitochondrial remodeling that differentially regulates T. gondii intracellular growth. Mitochondrial dysfunction with reduced ATP production is associated with impaired parasite invasion and growth in HFF, whereas mitochondrial adaptation with increased ATP production in Vero cells is associated ...
Musfika Tasnim Shirin +4 more
wiley +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Mapping the interactions between ATP and the sarcoplasmic reticulum Ca 2 + -ATPase with ATP and ATP analogs studied by Fourier transform infrared spectroscopy [PDF]
Die Infrarotspektroskopie in Verbindung mit photoaktivierbaren Substraten wurde zur Untersuchung von Substrat-Protein-Wechselwirkungen eingesetzt. Dabei wurden Konformationsänderungen der Ca2+-ATPase des Sarkoplasmatischen Retikulums bei Bindung des ...
Liu, Man
core
ATP-dependent chromatosome remodeling [PDF]
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Chioda, Mariacristina +2 more
core +1 more source

