Results 41 to 50 of about 969,519 (271)

Association of leukocyte mitochondrial DNA copy number and inflammation with mortality among older adults

Communications Medicine
Background As the population ages, a rising mortality burden is attributed to deaths in older adults, particularly deaths from inflammation-related chronic non-communicable diseases. The synergism between aging and inflammation remains unclear.
I-Chien Wu, Chin-San Liu, Wen-Ling Cheng, Ta-Tsung Lin, Pei-Fen Chen   +4 more
doaj   +1 more source

Cannabidiol (CBD) Upregulates Vitamin D3 Receptors (VDRs) Expression That Modulates Cytokines (TNF-α, IL-6), Tissue Elasticity, Cellular Senescence, and Mitochondrial ATP Generation in Human and Rodent Cell Lines

Nutrition and Dietary Supplements, 2023
Mahendra Kumar Trivedi,1 Alice Branton,1 Dahryn Trivedi,1 Sambhu Mondal,2 Snehasis Jana2 1Trivedi Global, Inc, Research & Development, Henderson, Nevada, USA; 2Trivedi Science Research Laboratory Pvt.
Trivedi MK, Branton A, Trivedi D, Mondal S, Jana S   +4 more
doaj  

Colostrum fails to prevent bovine/camelid neonatal neutrophil damage from AFB1

Journal of Immunotoxicology, 2020
Exposure to environmental toxicants that affect the immune system and overall health of many mammals is mostly unavoidable. One of the more common substances is the mycotoxins, especially carcinogenic aflatoxin (AF)B1 which also causes immune suppression/
Sajad Najafi, Gholamreza Mohammadi, Mehrdad Mohri, Saman Hosseinkhani, Jalil Mehrzad   +4 more
doaj   +1 more source

Formoterol Acting via β2-Adrenoreceptor Restores Mitochondrial Dysfunction Caused by Parkinson’s Disease-Related UQCRC1 Mutation and Improves Mitochondrial Homeostasis Including Dynamic and Transport

Biology
Formoterol, a β2-adrenergic receptor (β2AR) agonist, shows promise in various diseases, but its effectiveness in Parkinson’s disease (PD) is debated, with unclear regulation of mitochondrial homeostasis.
Jui-Chih Chang, Huei-Shin Chang, Yi-Chun Chao, Ching-Shan Huang, Chin-Hsien Lin, Zhong-Sheng Wu, Hui-Ju Chang, Chin-San Liu, Chieh-Sen Chuang   +8 more
doaj   +1 more source

Closing a Key Gap in DSCSA Compliance with Credentialing

Blockchain in Healthcare Today, 2023
In this session, the Open Credentialing Initiative (OCI) introduces the concept and practical application of electronic credentials. The audience will learn about their use in the context of DSCSA and how they enable timely compliance with the DSCSA ...
Bob Celeste, David Kessler
doaj   +1 more source

ATP-dependent chromatosome remodeling [PDF]

, 2008
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Chioda, Mariacristina, Becker, Peter B., Maier, Verena K.   +2 more
core   +1 more source

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2826-2842, May 2026.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu, Zhifu Xing, Jiao Li, Tangbing Yang, Huan Wu, Qiangsheng Ge, Yanju Wang, Baoan Song, Runjiang Song   +8 more
wiley   +1 more source

KIAA0753 promotes glucose and energy metabolism in osteoblasts inhibited by diabetes

陆军军医大学学报
Objective To explore the effect of KIAA0753 on glucose and energy metabolism in mouse embryonic osteoblast precursor cell line MC3T3-E1. Methods The GSE182286 datasets of patients with Joubert syndrome acquired from the Gene Expression Comprehensive ...
LI Mengxue, LI Mengxue, WANG Jichun, WANG Jichun, LI Letai   +4 more
doaj   +1 more source

External validation of the Ramathibodi paroxysmal supraventricular tachycardia recurrence score and development of a refined prediction model in a Hong Kong emergency department adult cohort: A retrospective study

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 2, April 2026.
Abstract Background Paroxysmal supraventricular tachycardia (PSVT) recurrence after adenosine treatment is common in emergency departments (EDs), but predictive tools require validation. Objectives To externally validate the Ramathibodi PSVT recurrence score in a Hong Kong ED cohort and develop a refined local model for predicting 24‐h recurrence ...
Man Yu Chan
wiley   +1 more source

A new electoral bottom-up model of institutional governance

Scientific Reports
The sustainable governance of Global Risky Commons (GRC)—global commons in the presence of a sizable risk of overall failure—is ubiquitous and requires a global solution. A prominent example is the mitigation of the adverse effects of global warming.
Carlos M. Garrido, Francisco C. Santos, Elias Fernández Domingos, Ana M. Nunes, Jorge M. Pacheco   +4 more
doaj   +1 more source