Results 61 to 70 of about 1,445,221 (211)

Distinct profiles of mitochondrial bioenergetics and redox balance in left atrial and ventricular myocardium in the healthy rat heart

Experimental Physiology, Volume 111, Issue 3, Page 1058-1068, 1 March 2026.
Abstract The left ventricle (LV) is the primary pumping chamber of the heart, generating high systolic pressure to sustain systemic circulation. LV contractile dysfunction is a hallmark of various cardiovascular diseases and is associated with mitochondrial dysfunction, characterised by decreased oxidative phosphorylation (OXPHOS) capacity and ...
Tingting Fang, Alex Chan, Janice Chew‐Harris, Toan Pham   +3 more
wiley   +1 more source

The Role of Heat Shock Protein 70 kDa in Asthma

Journal of Asthma and Allergy, 2021
Marina Shevchenko,1 Ekaterina Servuli,1,2 Zarema Albakova,1,3 Leonid Kanevskiy,1 Alexander Sapozhnikov1,3 1Department of Immunology, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia; 2Department of ...
Shevchenko M, Servuli E, Albakova Z, Kanevskiy L, Sapozhnikov A   +4 more
doaj  

Requirement of a Membrane Potential for the Posttranslational Transfer of Proteins into Mitochondsria [PDF]

, 1982
Posttranslational transfer of most precursor proteins into mitochondria is dependent on energization of the mitochondria. Experiments were carried out to determine whether the membrane potential or the intramitochondrial ATP is the immediate energy ...
Conboy J. G., Cote C., Daniels C. J., Data T., Date T., Enequist H. G., Graven S. N., Hallermayer G., Harmey M. A., Harmey M. A., Heldt H. W., Heytler P. G., Josefson L. G., Kekssler S. W., Korb H., Kovac L., Laemmli U. K., Lambowitz A. M., Lambowitz A. M., Maccechini M.-L., Matsuura S., Michel R., Mori M., Mori M., Nelson N., Passarella S., Pelham H. R. B., Raymond Y., Sebald W., Sebald W., Stigall D. L., Subik J., Tzagoloff A., Vignais P. V., Weiss H., Zimmermann R., Zimmermann R., Zimmermann R.   +37 more
core   +1 more source

Deficiency of Microglial‐Derived Spp1 Exacerbates Age‐Related Memory Decline by Impairing Mitochondrial Complex I Function

Aging Cell, Volume 25, Issue 2, February 2026.
Microglia‐derived Spp1 regulates OXPHOS via the AKT/Complex I pathway to mitigate age‐related memory decline. (Graphical Abstract was created using BioRender). ABSTRACT Age‐related memory decline is a hallmark of brain aging and a primary risk factor for neurodegenerative disorders.
Meiling Wang, Yumin Chang, Aojie He, Jing Yang, Ang Li, Hongqin Wang, Kah‐Leong Lim, Xing Guo, Chengwu Zhang, Li Lu   +9 more
wiley   +1 more source

Comportamento do sistema de aterramento de LDs 69 kV com estruturas de concreto sob descargas atmosféricas

Revista Principia, 2013
Este trabalho analisa o comportamento do sistema de aterramento de Linhas de Distribuição de 69kV com estruturas de concreto dotadas de cabo para-raios quando submetidas a descargas atmosféricas. Neste estudo, foram modelados com a utilização do software
Antonio dos Santos Dália, Franklin Martins Pamplona, José Tavares de Oliveira   +2 more
doaj   +1 more source

A new type of Na+-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif [PDF]

, 2013
: The anaerobic bacterium Fusobacterium nucleatum uses glutamate decarboxylation to generate a transmembrane gradient of Na+. Here, we demonstrate that this ion-motive force is directly coupled to ATP synthesis, via an F1Fo-ATP synthase with a novel Na ...
Faraldo-Gómez, José D., Iglesias-Cans, Marina, Krah, Alexander, Leone, Vanessa, M. Cook, Gregory, Matthies, Doreen, Meier, Thomas, Schulz, Sarah, Yildiz, Özkan   +8 more
core   +3 more sources

Photo‐Empowered Macrophage‐Based Drug Delivery System Overcomes Motility Suppression and Significantly Enhances Deep Tumor Drug Delivery

Advanced Science, Volume 13, Issue 5, 27 January 2026.
This study develops a photo‐empowered macrophage‐based (PEM) drug delivery system that provides a novel and effective solution for restoring cellular motility to enhance drug delivery and overcome hypoxia‐induced multidrug resistance. The construction of the PEM system fully exploits the unique biological properties of macrophages and the energy ...
Zhaoming Fu, Xin Cui, Shanshan Liu, Lu Gao, Yingang Sun, Yujun Chen, Mianlong Li, Yuxin Fan, Jing Kuang, Wen Song, Feifan Zhou   +10 more
wiley   +1 more source

Beneficial effects of PerformLyteTM, a prodosomed phytonutrient-enriched electrolyte formulation, in enhancing neuro-muscular synergy, immune competence, cellular aerobic glycolysis and sports performance [PDF]

BIO Web of Conferences
An optimised sports nutrition formulation achieving the correct blend of electrolytes with antioxidants and vitamins is integral towards meeting the demanding performance in professional sports arena.
William Downs Bernard, Banik Samudra P., Morrison Bruce S., Chakraborty Tandra, Bagchi Manashi, Chakraborty Sanjoy, Kushner Steve, Bagchi Debasis   +7 more
doaj   +1 more source

ATP mediates both activation and inhibition of K(ATP) channel activity via cAMP-dependent protein kinase in insulin-secreting cell lines. [PDF]

, 1989
The single-channel recording technique was employed to investigate the mechanism conferring ATP sensitivity to a metabolite-sensitive K channel in insulin-secreting cells.
Ciani, S, Eddlestone, GT, Ribalet, B
core  

Deficient Cardiolipin Remodelling Alters Muscle Fibre Composition and Neuromuscular Connectivity in Barth Syndrome

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Barth syndrome (BTHS) is a rare X‐linked mitochondrial disorder caused by mutations in the TAFAZZIN gene, which disrupts cardiolipin (CL) remodelling and mitochondrial function. While cardiac manifestations of BTHS are well characterized in male patients, the mechanisms underlying skeletal muscle weakness and fatigability are poorly
Catalina Matias, Paige L. Snider, Elizabeth A. Sierra Potchanant, Joshua R. Huot, Rahul Raghav, Michael T. Chin, Simon J. Conway, Jeffrey J. Brault   +7 more
wiley   +1 more source