Results 51 to 60 of about 759,738 (176)
ATP Cellotoxicity, ATP-Induced Cell Death and ATP Depletion
This paper delves into three pivotal themes concerning adenosine triphosphate (ATP): ATP cytotoxicity, ATP-induced cell death, and ATP depletion. Initially, we scrutinize ATP's involvement in cytotoxicity, with a specific focus on elucidating the mechanisms underlying cell demise triggered by augmented extracellular ATP concentrations. Subsequently, we
Haoling Zhang +6 more
openaire +1 more source
Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu +5 more
wiley +1 more source
Yanfang Zhang, Lirong Gong, Yuan Zhang, Shuan Dong, Jia Shi, Xiangyun Li, Yan Guo, Simeng He, Xiaoyang Wu, Shasha Liu, Huayang Liu, Lantian Zhang, Jianbo Yu Department of Anesthesiology and Critical Care Medicine, Tianjin Nankai Hospital, Tianjin Medical
Zhang Y +12 more
doaj
Abstract The left ventricle (LV) is the primary pumping chamber of the heart, generating high systolic pressure to sustain systemic circulation. LV contractile dysfunction is a hallmark of various cardiovascular diseases and is associated with mitochondrial dysfunction, characterised by decreased oxidative phosphorylation (OXPHOS) capacity and ...
Tingting Fang +3 more
wiley +1 more source
Microglia‐derived Spp1 regulates OXPHOS via the AKT/Complex I pathway to mitigate age‐related memory decline. (Graphical Abstract was created using BioRender). ABSTRACT Age‐related memory decline is a hallmark of brain aging and a primary risk factor for neurodegenerative disorders.
Meiling Wang +9 more
wiley +1 more source
BIOREMEDIATION OF CADMIUM CONTAMINATED WATER: BACTERIAL ACCUMULATION AND SURFACE COMPLEXITY BY REVIBACILLUS AGRI C15 AND BREVIBACILLUS AGRI C15 CDR [PDF]
Brevibacillus agri C15 and Brevibacillus agri C15 CdR have been reported as a tool for do uptake of cadmium (Cd). Nevertheless, it is unclear whether these strains contrast in their adsorption behaviors and surface complexation could be one of the ...
N. M. T. Jebril, A. K. Murad, R. Boden
doaj +1 more source
This study develops a photo‐empowered macrophage‐based (PEM) drug delivery system that provides a novel and effective solution for restoring cellular motility to enhance drug delivery and overcome hypoxia‐induced multidrug resistance. The construction of the PEM system fully exploits the unique biological properties of macrophages and the energy ...
Zhaoming Fu +10 more
wiley +1 more source
The effectiveness of human SAGE medium compared to other conventional culture media on the ovine early embryonic development, in vitro [PDF]
Developing an optimal in vitro embryo culture medium with high blastocyst rates and good-quality embryos remains challenging and controversial, as most culture media directly impact mammalian embryonic development.
Saif O. Al-Hafedh +2 more
doaj +1 more source
ABSTRACT Purpose Mammalian sperm require a large amount of ATP to sustain motility. While glycolysis and oxidative phosphorylation (OXPHOS) are established ATP sources, they cannot fully explain motility maintenance under glucose‐deprived conditions.
Kosei Oishi +9 more
wiley +1 more source
Fondová schémata jako možná řešení finanční udržitelnosti dánského penzijního systému
The financial sustainability of pension systems is one of the crucial topics in the context of population aging. The issue of financial sustainability is primarily associated with public unfunded pension schemes, where there is an increase in future ...
Jan Pokorný, Pavlína Hejduková
doaj +1 more source

