Results 51 to 60 of about 969,519 (271)
Background. Histamine is one of the versatile biogenic amines with multiple roles in the immune response and allergic disorders. Histamine and ATP can act as ligands in the body.
Nataliya Harasym +5 more
doaj +1 more source
A KATP channel opener inhibited myocardial reperfusion action potential shortening and arrhythmias [PDF]
Low concentrations of certain K<sub>ATP</sub> channel openers have been reported to exert a moderate inhibitory effect on arrhythmias during post-ischaemic early myocardial reperfusion, but the accompanying effects on the time course of ...
Northover, B.J. +5 more
core +1 more source
Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei +9 more
wiley +1 more source
Acetyl phosphate (AcP) is generally produced from acetyl coenzyme A by phosphotransacetylase (Pta), and subsequent reaction with ADP, catalyzed by acetate kinase (Ack), produces ATP.
Yasuo Yoshida +4 more
doaj +1 more source
Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of the
Luke Tattersall +5 more
doaj +1 more source
Purinergic ATP‐P2X7 Signaling Drives Colonic Giant Migrating Contraction in Suncus murinus
Using Suncus murinus, this study reveals that ATP regulates colonic giant migrating contractions (GMCs). ATP activates P2X7 receptors on cholinergic neurons, triggering powerful contractions that facilitate defecation. This effect is suppressed by P2X7 receptor antagonists and atropine, identifying the ATP‐P2X7‐acetylcholine axis as a key regulatory ...
Ayano Gomi +2 more
wiley +1 more source
The Role of Heat Shock Protein 70 kDa in Asthma
Marina Shevchenko,1 Ekaterina Servuli,1,2 Zarema Albakova,1,3 Leonid Kanevskiy,1 Alexander Sapozhnikov1,3 1Department of Immunology, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia; 2Department of ...
Shevchenko M +4 more
doaj
Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu +5 more
wiley +1 more source
Expression of Concern: Oxidative stress influences cholesterol efflux in THP-1 macrophages: Role of ATP-binding cassette A1 and nuclear factors [PDF]
openalex +1 more source
Este trabalho analisa o comportamento do sistema de aterramento de Linhas de Distribuição de 69kV com estruturas de concreto dotadas de cabo para-raios quando submetidas a descargas atmosféricas. Neste estudo, foram modelados com a utilização do software
Antonio dos Santos Dália +2 more
doaj +1 more source

