Results 1 to 10 of about 2,126,685 (298)
Self-organized enhancement of conductivity in biological ion channels [PDF]
, 2013 We discuss an example of self-organisation in a biological system. It arises from long-range ion-ion interactions, and it leads us to propose a novel mechanism of enhanced conduction in ion channels.
Kaufman, Igor +5 more
core +6 more sources
Membranes, 2023 In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska +3 more
doaj +1 more source
British Journal of Pharmacology, 2007 ALEXANDER, S.P.H., MATHIE, A. & PETERS, J.A. (2007). Guide to Receptors and Channels (GRAC), 2nd edition (2007 revision). Br. J. Pharmacol., 150 (Suppl. 1), S1–S168.
S P H Alexander, A Mathie, J A Peters
openaire +3 more sources
Non-equilibrium stochastic dynamics of open ion channels [PDF]
, 2013 We present and discuss a modified version of reaction rate theory (RRT) to describe the passage of a positive ion through a biological ion channel. It takes explicit account of the non-equilibrium nature of the permeation process. Unlike traditional RRT,
Kaufman, Igor +5 more
core +4 more sources
Alternative Targets for Modulators of Mitochondrial Potassium Channels
Molecules, 2022 Mitochondrial potassium channels control potassium influx into the mitochondrial matrix and thus regulate mitochondrial membrane potential, volume, respiration, and synthesis of reactive oxygen species (ROS).
Antoni Wrzosek +4 more
doaj +1 more source
Photocatalytic Isomerization of (E)-Anethole to (Z)-Anethole
Molecules, 2022 Natural product (E)-anethole was isomerized to (Z)-anethole in a photocatalytic reaction. For this purpose, a self-designed cheap photoreactor was constructed.
Marvin Korff +4 more
doaj +1 more source
Molecules, 2021 Mitochondria play a key role in energy metabolism within the cell. Potassium channels such as ATP-sensitive, voltage-gated or large-conductance Ca2+-regulated channels have been described in the inner mitochondrial membrane.
Aleksandra Sek +4 more
doaj +1 more source
Diabetologia, 1992 Insulin secretion by the pancreatic Beta cell is dependent upon transmembrane ion fluxes gated by the ATP-regulated potassium channel and the voltage regulated, L-type calcium channel. This work group examined major recent advances in the structure and modulation of ion channels and how those advances may pertain to the physiology of insulin secretion ...
W, Catterall, P N, Epstein
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Thorax, 2013 Effective therapies for the 10% of patients with 'severe' asthma remain elusive, while other pulmonary diseases such as idiopathic pulmonary fibrosis are currently untreatable. Many cellular processes rely heavily on signals delivered by changes in the intracellular-free Ca(2+) concentration, in many cases relying on Ca(2+) influx from the ...
Peter, Bradding, Heike, Wulff
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Mitochondrial Potassium Channels as Druggable Targets
Biomolecules, 2020 Mitochondrial potassium channels have been described as important factors in cell pro-life and death phenomena. The activation of mitochondrial potassium channels, such as ATP-regulated or calcium-activated large conductance potassium channels, may have ...
Antoni Wrzosek +3 more
doaj +1 more source