Results 21 to 30 of about 804,799 (296)
Multiple Thresholds in a Model System of Noisy Ion Channels [PDF]
Voltage-activated ion channels vary randomly between open and closed states, influenced by the membrane potential and other factors. Signal transduction is enhanced by noise in a simple ion channel model.
D. Johnston +5 more
core +1 more source
Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]
The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model.
Chow C C +17 more
core +2 more sources
Calcium-permeable ion channels in control of autophagy and cancer
Autophagy, or cellular self-eating, is a tightly regulated cellular pathway the main purpose of which is lysosomal degradation and subsequent recycling of cytoplasmic material to maintain normal cellular homeostasis.
Artem eKondratskyi +5 more
doaj +1 more source
Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran +5 more
core +2 more sources
Mitochondria are involved in multiple cellular tasks, such as ATP synthesis, metabolism, metabolite and ion transport, regulation of apoptosis, inflammation, signaling, and inheritance of mitochondrial DNA. The majority of the correct functioning of mitochondria is based on the large electrochemical proton gradient, whose component, the inner ...
Szabo I., Szewczyk A.
openaire +2 more sources
The objective of this historical review is to recall the development of the field of synthetic ion channels over the past three decades. The most inspiring and influential breakthroughs with regard to structure and function are brought together to give the general reader an easily accessible understanding of the field.
Sakai Naomi, Matile Stefan
openaire +4 more sources
P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King +29 more
core +1 more source
Ion channel activity drives ion channel expression [PDF]
During embryonic development, excitable cells acquire a repertoire of ion channels that finely tune their electrical properties. Although the mechanisms by which an excitable cell selects its complement of ion channels are poorly defined, cell-autonomous as well as non-autonomous programmes of differentiation have been implicated.
openaire +2 more sources
Evolving theoretical descriptions of heavy-ion fusion :from phenomenological to microscopic approaches [PDF]
We overview the current status of theoretical approaches for heavy-ion fusion reactions at subbarrier energies. We particularly discuss theoretical challenges in the coupled-channels approach, that include i) a description of deep subbarrier hindrance of
Hagino, K.
core +2 more sources
The analysis of the molecular basis of the inherited cardiac arrhythmias has been the driving force behind the identification of the ion channels that generate the action potential. The genes encoding all the major ion channels have cloned and sequenced. The studies have revealed greater complexity than heretofore imagined.
openaire +2 more sources

