Results 21 to 30 of about 2,126,685 (298)
Langmuir, 2013 The objective of this historical review is to recall the development of the field of synthetic ion channels over the past three decades. The most inspiring and influential breakthroughs with regard to structure and function are brought together to give the general reader an easily accessible understanding of the field.
Sakai Naomi, Matile Stefan
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Journal of Biological Physics, 2003 We review the basic physics involved in transport of ions across membrane channels in cells. Electrochemical forces that control the diffusion of ions are discussed both from microscopic and macroscopic perspectives. A case is made for use of Brownian dynamics as the minimal phenomenological model that provides a bridge between experiments and more ...
Kuyucak, Serdar, Bastug, Turgut
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Ion channels and ion selectivity [PDF]
Essays in Biochemistry, 2017 Specific macromolecular transport systems, ion channels and pumps, provide the pathways to facilitate and control the passage of ions across the lipid membrane. Ion channels provide energetically favourable passage for ions to diffuse rapidly and passively according to their electrochemical potential.
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Receptors and Ion Channels [PDF]
Journal of Experimental Biology, 1986 ABSTRACT Receptors and ion channels are membrane-bound proteins involved in fundamental regulatory mechanisms in cells. They govern both a cell’s homeostatic activity and its programmed responses to intra- and extracellular stimuli. Specific receptor molecules in a cell’s plasma membrane can be activated by signal molecules present ...
P D, Evans, I B, Levitan
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Charge fluctuations and boundary conditions of biological ion channels : effect on the ionic transition rate [PDF]
, 2009 A self-consistent solution is derived for the Poisson-Nernst-Planck (PNP) equation, valid both inside a biological ion channel and in the adjacent bulk fluid. An iterative procedure is used to match the two solutions together at the channel mouth. Charge
Luchinsky, D. G. +3 more
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PTPRM Is Critical for Synapse Formation Regulated by Zinc Ion
Frontiers in Molecular Neuroscience, 2022 In the nervous system, the trace metal ion zinc is required for normal mammalian brain development and physiology. Zinc homeostasis is essential for the control of physiological and pathophysiological brain functions.
Xiaoqiang Mo +8 more
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Ion channel activity drives ion channel expression [PDF]
The Journal of Physiology, 1998 During embryonic development, excitable cells acquire a repertoire of ion channels that finely tune their electrical properties. Although the mechanisms by which an excitable cell selects its complement of ion channels are poorly defined, cell-autonomous as well as non-autonomous programmes of differentiation have been implicated.
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A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer
Frontiers in Physiology, 2019 Cell migration is a key process in cancer metastasis, allowing malignant cells to spread from the primary tumor to distant organs. At the molecular level, migration is the result of several coordinated events involving mechanical forces and cellular ...
Jimena Canales +14 more
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Ubiquitylation of Ion Channels
Physiology, 2005 Ubiquitylation (i.e., covalent attachment of ubiquitin moieties to proteins) of ion channels allows regulation of their activity and fate. Nedd4/Nedd4-like ubiquitin-protein ligases bind to, ubiquitylate, and modulate the internalization of several channels bearing PY motifs, whereas endoplasmic reticulum-associated degradation (involving ...
Abriel H, Staub O
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