Results 1 to 10 of about 35,721 (282)

Function of TRP channels in monocytes/macrophages [PDF]

open access: yesFrontiers in Immunology, 2023
The transient receptor potential channel (TRP channel) family is a kind of non- specific cation channel widely distributed in various tissues and organs of the human body, including the respiratory system, cardiovascular system, immune system, etc.
Jiangbo Wu   +33 more
doaj   +4 more sources

TRP channels in schistosomes

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2016
Praziquantel (PZQ) is effectively the only drug currently available for treatment and control of schistosomiasis, a disease affecting hundreds of millions of people worldwide.
Swarna Bais, Robert M. Greenberg
doaj   +4 more sources

TRP Channels in Excitotoxicity. [PDF]

open access: yesNeuroscientist
Glutamate excitotoxicity is a central mechanism contributing to cellular dysfunction and death in various neurological disorders and diseases, such as stroke, traumatic brain injury, epilepsy, schizophrenia, addiction, mood disorders, Huntington\u27s ...
Zong P, Legere N, Feng J, Yue L.
europepmc   +4 more sources

TRP Channels in Human Prostate [PDF]

open access: yesThe Scientific World Journal, 2010
This review gives an overview of morphological and functional characteristics in the human prostate. It will focus on the current knowledge about transient receptor potential (TRP) channels expressed in the human prostate, and their putative role in ...
Carl Van Haute   +2 more
doaj   +3 more sources

The regulatory and modulatory roles of TRP family channels in malignant tumors and relevant therapeutic strategies

open access: yesActa Pharmaceutica Sinica B, 2022
Transient receptor potential (TRP) channels are one primary type of calcium (Ca2+) permeable channels, and those relevant transmembrane and intracellular TRP channels were previously thought to be mainly associated with the regulation of cardiovascular ...
Tiecheng Zhong   +7 more
doaj   +3 more sources

Cannabinoid Ligands Targeting TRP Channels [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2019
Transient receptor potential (TRP) channels are a group of membrane proteins involved in the transduction of a plethora of chemical and physical stimuli.
Chanté Muller   +2 more
doaj   +4 more sources

TRP Channels in Cancer: Signaling Mechanisms and Translational Approaches [PDF]

open access: yesBiomolecules, 2023
Ion channels play a crucial role in a wide range of biological processes, including cell cycle regulation and cancer progression. In particular, the transient receptor potential (TRP) family of channels has emerged as a promising therapeutic target due ...
Matilde Marini   +5 more
doaj   +2 more sources

TRP channels and breast cancer: the role of TRPs in the pathophysiological development [PDF]

open access: yesFrontiers in Molecular Biosciences
TRP channels play important roles in regulating various physiological and pathological processes, including the progression of cancer. Several TRP channels mediate tumour development.
Yu Zhang   +4 more
doaj   +2 more sources

A Comprehensive Review on the Regulatory Action of TRP Channels: A Potential Therapeutic Target for Nociceptive Pain [PDF]

open access: yesNeuroscience Insights, 2023
The transient receptor potential (TRP) superfamily of ion channels in humans comprises voltage-gated, non-selective cation channels expressed both in excitable as well as non-excitable cells. Four TRP channel subunits associate to create functional homo-
Santosh Anand, Senthilkumar Rajagopal
doaj   +2 more sources

TRP channels: Role in neurodegenerative diseases and therapeutic targets [PDF]

open access: yesHeliyon, 2023
TRP (Transient receptor potential) channels are integral membrane proteins consisting of a superfamily of cation channels that allow permeability of both monovalent and divalent cations. TRP channels are subdivided into six subfamilies: TRPC, TRPV, TRPM,
Mashoque Ahmad Rather   +6 more
doaj   +2 more sources

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