Results 1 to 10 of about 65,940 (289)
TRP Channels Mediated Pathological Ca2+-Handling and Spontaneous Ectopy
Frontiers in Cardiovascular Medicine, 2019 Ion channel biology offers great opportunity in identifying and learning about cardiac pathophysiology mechanisms. The discovery of transient receptor potential (TRP) channels is an add-on to the opportunity. Interacting with numerous signaling pathways,
Martin Ezeani
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Role of Oxidative Stress and Ca2+ Signaling in Psychiatric Disorders
Frontiers in Cell and Developmental Biology, 2021 Psychiatric disorders are caused by complex and diverse factors, and numerous mechanisms have been proposed for the pathogenesis of these disorders.
Akito Nakao +3 more
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Ion channel expression in human melanoma samples. in silico identification and experimental validation of molecular targets [PDF]
, 2019 Expression of 328 ion channel genes was investigated, by in silico analysis, in 170 human melanoma samples and controls. Ninety-one members of this gene-family (i.e., about 28%) show a significant (p 0.90 and p 90% in most cases).
D’Arcangelo, Daniela +5 more
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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 The progression of cells from a normal differentiated state in which rates of proliferation and apoptosis are balanced to a tumorigenic and metastatic state involves the accumulation of mutations in multiple key signalling proteins and the evolution and clonal selection of more aggressive cell phenotypes. These events are associated with changes in the
Prevarskaya, Natalia +2 more
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HeliyonTransient Receptor Potential (TRP) channels are a family of ion channels that play pivotal roles in various physiological processes, including sensory transduction, temperature regulation, and inflammation.
Varunya Chantadul +3 more
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A structural view of ligand-dependent activation in thermoTRP channels
Frontiers in Physiology, 2014 Transient Receptor Potential (TRP) proteins are a large family of ion channels, grouped intoseven sub-families. Although great advances have been made regarding the activation andmodulation of TRP channel activity, detailed molecular mechanisms governing
Ximena eSteinberg +3 more
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Combining mass spectrometry and genetic labeling in mice to report TRP channel expression
MethodsX, 2022 Transient receptor potential (TRP) ion channels play important roles in fundamental biological processes throughout the body of humans and mice. TRP channel dysfunction manifests in different disease states, therefore, these channels may represent ...
Philipp Wartenberg +8 more
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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 Pulmonary and systemic arterial hypertension are associated with profound alterations in Ca(2+) homeostasis and smooth muscle cell proliferation. A novel class of non-selective cation channels, the transient receptor potential (TRP) channels, have emerged at the forefront of research into hypertensive disease states.
Firth, Amy L. +2 more
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BiomoleculesChronic itch is a debilitating condition with limited treatment options, severely affecting quality of life. The identification of pruriceptors has sparked a growing interest in the therapeutic potential of TRP channels in the context of itch.
Eun Jin Go +3 more
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Dietary supplementation of essential oils in dairy cows: evidence for stimulatory effects on nutrient absorption [PDF]
, 2019 Results of recent in vitro experiments suggest that essential oils (EO) may not only influence ruminal fermentation but also modulate the absorption of cations like Na+, Ca2+ and NH4+ across ruminal epithelia of cattle and sheep through direct ...
Braun, H.-S. +4 more
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