Results 1 to 10 of about 13,051 (119)
The Role of TRPA1 Channels in Thermosensation
Cell Insight, 2022 Transient receptor potential ankyrin 1 (TRPA1) is a polymodal nonselective cation channel sensitive to different physical and chemical stimuli. TRPA1 is associated with many important physiological functions in different species and thus is involved in ...
Ren Lai, Peter Kamau
exaly +3 more sources
The Journal of Poultry Science, 2022 The pungency induced by spices and herbs plays an important role in food choice and appetite, and it is suggested that adding spices and herbs to feed as natural alternatives to antibiotics has beneficial effects in poultry farming.
Fuminori Kawabata +5 more
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Methylglyoxal evokes pain by stimulating TRPA1. [PDF]
PLoS ONE, 2013 Diabetic neuropathy is a severe complication of long-standing diabetes and one of the major etiologies of neuropathic pain. Diabetes is associated with an increased formation of reactive oxygen species and the electrophilic dicarbonyl compound ...
David A Andersson +7 more
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Czech Journal of Animal Science, 2012 Thymol's antimicrobial properties urged researchers to study its effect on animal performance and intestinal health in pigs. However, thymol has the characteristic sharp odor of thyme and a bitter, aromatic, and sometimes burning sensation which may ...
J. Michiels +5 more
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TRPA1 is functionally expressed primarily by IB4-binding, non-peptidergic mouse and rat sensory neurons. [PDF]
PLoS ONE, 2012 Subpopulations of somatosensory neurons are characterized by functional properties and expression of receptor proteins and surface markers. CGRP expression and IB4-binding are commonly used to define peptidergic and non-peptidergic subpopulations.
Marie E Barabas +2 more
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Is Capsaicin a Pain Inducer or Killer? A Review of its Related Mechanisms [PDF]
المجلة العراقية للصيدلةBackground: Capsaicin is the chemical responsible for the hot and irritating characteristics of chili peppers. Because it produces both heat and pain, this phytochemical is a valuable means of scientific investment for pain research. Aim: This study
Ayman Faris Faisal +3 more
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TRPA1 as a O2 sensor detects microenvironmental hypoxia in the mice anterior cingulate cortex
Scientific Reports, 2023 Transient receptor potential ankyrin 1 (TRPA1) is a member of the TRP channel family and is expressed in peripheral and central nervous systems. In the periphery, TRPA1 senses cold and pain. However, the functions of TRPA1 in the CNS are unclear.
Ryo Kawabata +5 more
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Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke
eLife, 2018 Hypoxia and ischemia are linked to oxidative stress, which can activate the oxidant-sensitive transient receptor potential ankyrin 1 (TRPA1) channel in cerebral artery endothelial cells, leading to vasodilation.
Paulo Wagner Pires, Scott Earley
doaj +1 more source
Application of PASS Algorithm for the Discovery of New Trpa1 Antagonists
Proceedings, 2019 TRPA1 is a calcium ion channel found on the plasma membrane of many animal cells and it is [...]
Trif Comin +4 more
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Dexmedetomidine protects against ischemia and reperfusion-induced kidney injury in rats by inhibiting the expression of TRPM2 and TRPA1 channels [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Renal ischemia and reperfusion (I/R) injury is a potentially serious issue encountered during various medical and surgical procedures. This condition is clinically significant because of its high incidence and mortality rate. In this study,
Abdulkadir Uzunboy +5 more
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