Results 11 to 20 of about 12,428 (199)
The Journal of Poultry Science, 2022 The pungency induced by spices and herbs plays an important role in food choice and appetite, and it is suggested that adding spices and herbs to feed as natural alternatives to antibiotics has beneficial effects in poultry farming.
Fuminori Kawabata +5 more
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Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity [PDF]
Nature Communications, 2013 Transient receptor potential ankyrin 1 (TRPA1) protein is a nonselective cation channel. Although many studies suggest that TRPA1 is involved in inflammatory and neuropathic pain, its mechanism remains unclear. Here we identify an alternative splice variant of the mouse Trpa1 gene.
Zhou, Yiming +3 more
openaire +4 more sources
TRPA1: A Gatekeeper for Inflammation [PDF]
Annual Review of Physiology, 2013 Tissue damage evokes an inflammatory response that promotes the removal of harmful stimuli, tissue repair, and protective behaviors to prevent further damage and encourage healing. However, inflammation may outlive its usefulness and become chronic. Chronic inflammation can lead to a host of diseases, including asthma, itch, rheumatoid arthritis, and ...
Diana M, Bautista +2 more
openaire +2 more sources
Methylglyoxal evokes pain by stimulating TRPA1. [PDF]
PLoS ONE, 2013 Diabetic neuropathy is a severe complication of long-standing diabetes and one of the major etiologies of neuropathic pain. Diabetes is associated with an increased formation of reactive oxygen species and the electrophilic dicarbonyl compound ...
David A Andersson +7 more
doaj +1 more source
Czech Journal of Animal Science, 2012 Thymol's antimicrobial properties urged researchers to study its effect on animal performance and intestinal health in pigs. However, thymol has the characteristic sharp odor of thyme and a bitter, aromatic, and sometimes burning sensation which may ...
J. Michiels +5 more
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Is Capsaicin a Pain Inducer or Killer? A Review of its Related Mechanisms [PDF]
المجلة العراقية للصيدلةBackground: Capsaicin is the chemical responsible for the hot and irritating characteristics of chili peppers. Because it produces both heat and pain, this phytochemical is a valuable means of scientific investment for pain research. Aim: This study
Ayman Faris Faisal +3 more
doaj +1 more source
TRPA1 as a O2 sensor detects microenvironmental hypoxia in the mice anterior cingulate cortex
Scientific Reports, 2023 Transient receptor potential ankyrin 1 (TRPA1) is a member of the TRP channel family and is expressed in peripheral and central nervous systems. In the periphery, TRPA1 senses cold and pain. However, the functions of TRPA1 in the CNS are unclear.
Ryo Kawabata +5 more
doaj +1 more source
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. [PDF]
PLoS ONE, 2012 BACKGROUND: The transient receptor potential ankyrin 1 (TRPA1) channel, localized to airway sensory nerves, has been proposed to mediate airway inflammation evoked by allergen and cigarette smoke (CS) in rodents, via a neurogenic mechanism.
Romina Nassini +15 more
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TRPA1 is functionally expressed primarily by IB4-binding, non-peptidergic mouse and rat sensory neurons. [PDF]
PLoS ONE, 2012 Subpopulations of somatosensory neurons are characterized by functional properties and expression of receptor proteins and surface markers. CGRP expression and IB4-binding are commonly used to define peptidergic and non-peptidergic subpopulations.
Marie E Barabas +2 more
doaj +1 more source
Frontiers in Oncology, 2021 Melanoma skin cancer is extremely aggressive with increasing incidence and mortality. Among the emerging therapeutic targets in the treatment of cancer, the family of transient receptor potential channels (TRPs) has been reported as a possible ...
Maria Fernanda Forni +7 more
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