Effects of aging on calcium channels in skeletal muscle [PDF]
Frontiers in Molecular BiosciencesIn skeletal muscle, calcium is not only essential to stimulate and sustain their contractions but also for muscle embryogenesis, regeneration, energy production in mitochondria, and fusion.
Mingyi Dong, Andrés Daniel Maturana
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Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes. [PDF]
Frontiers in Immunology, 2013 In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou +4 more
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Electrophysiological Mechanisms and Therapeutic Potential of Calcium Channels in Atrial Fibrillation [PDF]
Reviews in Cardiovascular MedicineAtrial fibrillation (AF) is a prevalent and complex arrhythmia for which the pathogenesis involves various electrophysiological factors, notably the regulation of calcium channels.
Zuyuan Huang +3 more
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What calcium channels remember
eLife, 2023 A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release.
Thomas Kaas +2 more
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Calcium channels in anesthesia management: A molecular and clinical review [PDF]
Molecular PainCalcium channels play an essential role in the molecular and physiological mechanisms underlying anesthesia by mediating intracellular calcium ion (Ca 2+ ) flux, which regulates key processes such as neurotransmitter release, neuronal excitability, and ...
Mostafa Saberian +4 more
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The regulation role of calcium channels in mammalian sperm function: a narrative review with a focus on humans and mice [PDF]
PeerJMammalian sperm are characterized as specialized cells, as their transcriptional and translational processes are largely inactive. Emerging researches indicate that Ca2+ serves as a crucial second messenger in the modulation of various sperm ...
Yebin Yang +6 more
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Calcium channels as therapeutic targets in head and neck squamous cell carcinoma: current evidence and clinical trials [PDF]
Frontiers in OncologyHead and neck squamous cell carcinoma (HNSCC) originates from the mucosal epithelium of the oral cavity, pharynx, and larynx, and is marked by high rates of recurrence and metastasis.
Jinye Lin +6 more
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Calcium Channels in the Heart: Disease States and Drugs
Cells, 2022 Calcium ions are the major signaling ions in the cells. They regulate muscle contraction, neurotransmitter secretion, cell growth and migration, and the activity of several proteins including enzymes and ion channels and transporters. They participate in
Kajol Shah +4 more
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Frontiers in Physiology, 2022 Biochemical and functional studies of ion channels have shown that many of these integral membrane proteins form macromolecular signaling complexes by physically associating with many other proteins.
Kunal R. Shah +4 more
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Review the Regulation of Plasma Membrane Calcium Channel in Cancer and Patch Clamp Technique [PDF]
E3S Web of Conferences, 2021 As one of the most versatile and universal second messengers, calcium plays an essential role in cell life. Here we briefly reviewed the research progress of how different calcium channels are located at the cell plasma membrane, including voltage-gated ...
Chen Nanjun, Fang Qigeng
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