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Calcium Channels in the Heart: Disease States and Drugs
Calcium ions are the major signaling ions in the cells. They regulate muscle contraction, neurotransmitter secretion, cell growth and migration, and the activity of several proteins including enzymes and ion channels and transporters. They participate in
Kajol Shah +4 more
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Effects of aging on calcium channels in skeletal muscle [PDF]
In skeletal muscle, calcium is not only essential to stimulate and sustain their contractions but also for muscle embryogenesis, regeneration, energy production in mitochondria, and fusion.
Mingyi Dong, Andrés Daniel Maturana
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Electrophysiological Mechanisms and Therapeutic Potential of Calcium Channels in Atrial Fibrillation [PDF]
Atrial fibrillation (AF) is a prevalent and complex arrhythmia for which the pathogenesis involves various electrophysiological factors, notably the regulation of calcium channels.
Zuyuan Huang +3 more
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Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes.
In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou +4 more
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Calcium channels in anesthesia management: A molecular and clinical review [PDF]
Calcium channels play an essential role in the molecular and physiological mechanisms underlying anesthesia by mediating intracellular calcium ion (Ca 2+ ) flux, which regulates key processes such as neurotransmitter release, neuronal excitability, and ...
Mostafa Saberian +4 more
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Biochemical and functional studies of ion channels have shown that many of these integral membrane proteins form macromolecular signaling complexes by physically associating with many other proteins.
Kunal R. Shah +4 more
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What calcium channels remember
A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release.
Thomas Kaas +2 more
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Review the Regulation of Plasma Membrane Calcium Channel in Cancer and Patch Clamp Technique [PDF]
As one of the most versatile and universal second messengers, calcium plays an essential role in cell life. Here we briefly reviewed the research progress of how different calcium channels are located at the cell plasma membrane, including voltage-gated ...
Chen Nanjun, Fang Qigeng
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Calcium Permeable Channels in Cancer Hallmarks
Cancer, the second cause of death worldwide, is characterized by several common criteria, known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death resistance, angiogenesis, invasion and metastasis.
Sendoa Tajada, Carlos Villalobos
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Calcium Channels: Noteworthy Regulators and Therapeutic Targets in Dermatological Diseases
Dysfunctional skin barrier and impaired skin homeostasis may lead to or aggravate a series of dermatologic diseases. A large variety of biological events and bioactive molecules are involved in the process of skin wound healing and functional recovery ...
Min Wang +6 more
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