Results 11 to 20 of about 1,814,083 (253)

Structure and function of potassium and calcium channels [PDF]

open access: yes, 2005
In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
core   +9 more sources

TRPV5 and TRPV6 calcium-selective channels. [PDF]

open access: yes, 2017
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the ...
Hediger, Matthias   +3 more
core   +2 more sources

Tissue-specific expression of calcium channels [PDF]

open access: yes, 1993
The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Flockerzi, Veit   +3 more
core   +1 more source

The involvement of TRP channels in bone homeostasis

open access: yesFrontiers in Endocrinology, 2012
Calcium and bone homeostasis are intimately related. On the one hand, bone relies on a sufficient supply of calcium to maintain its structural and mechanical properties and thus largely depends on calcium absorption in the intestine and calcium ...
Liesbet eLieben, Geert eCarmeliet
doaj   +1 more source

Regulation of Presynaptic Calcium Channels by Synaptic Proteins

open access: yesJournal of Pharmacological Sciences, 2003
Calcium entry into nerve termini via voltage gated calcium channels is an essential step in neurotransmission. Consequently, second messenger regulation of calcium channel activity modulates synaptic activity.
Gerald W. Zamponi
doaj   +1 more source

Ion Channels of Pituitary Gonadotrophs and Their Roles in Signaling and Secretion

open access: yesFrontiers in Endocrinology, 2017
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium concentration.
Stanko S. Stojilkovic   +2 more
doaj   +1 more source

Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC

open access: yesMolecular Brain, 2019
This study describes the functional interaction between Cav3.2 calcium channels and the Epithelial Sodium Channel (ENaC). β-ENaC subunits showed overlapping expression with endogenous Cav3.2 calcium channels in the thalamus and hypothalamus as detected ...
Agustin Garcia-Caballero   +7 more
doaj   +1 more source

Modulation of Calcium Transients in Cardiomyocytes by Transient Receptor Potential Canonical 6 Channels

open access: yesFrontiers in Physiology, 2020
Transient receptor potential canonical 6 (TRPC6) channels are non-selective cation channels that are thought to underlie mechano-modulation of calcium signaling in cardiomyocytes.
Azmi A. Ahmad   +6 more
doaj   +1 more source

Suramin-Induced Neurotoxicity: Preclinical Models and Neuroprotective Strategies

open access: yesMolecules, 2018
Suramin is a trypan blue analogon originally developed to treat protozoan infections, which was found to have diverse antitumor effects. One of the most severe side effects in clinical trials was the development of a peripheral sensory-motor ...
David von der Ahe   +5 more
doaj   +1 more source

Presynaptic Calcium Channel Open Probability and Changes in Calcium Influx Throughout the Action Potential Determined Using AP-Waveforms

open access: yesFrontiers in Synaptic Neuroscience, 2020
Action potentials arriving at a nerve terminal activate voltage-gated calcium channels and set the electrical driving force for calcium entry which affects the amount and duration of neurotransmitter release.
Matthew S. Scarnati   +6 more
doaj   +1 more source

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