Results 11 to 20 of about 257,064 (311)
Pancreatic β Cell CaV Channels in Health and Disease [PDF]
Multiple types of voltage-gated calcium (CaV) channels including CaV1.2, CaV1.3, CaV2.1, CaV2.2, CaV2.3, CaV3.1, and CaV3.2 operate in electrically excitable β cells under both physiological and pathophysiological conditions.
Berggren, P-O +5 more
core +1 more source
Calcium channels in lymphocytes [PDF]
On B and T lymphocytes, ligation of the antigen receptor (AgR) induces a biphasic Ca2+ response. In the initial phase there is a large elevation in the intracellular Ca2+ concentration as a consequence of Ca2+ release from intracellular stores. This is followed by a lower, but prolonged elevation that is dependent on extracellular Ca2+.1,2 This simple ...
G, Grafton, L, Thwaite
openaire +2 more sources
Voltage-gated calcium channels (VGCCs) and estrogen receptors are important cellular proteins that have been shown to interact with each other across varied cells and tissues.
Yashashwini Dinesh Subbamanda +1 more
doaj +1 more source
Tissue-specific expression of calcium channels [PDF]
The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Flockerzi, Veit +3 more
core +1 more source
An integral view on calcium channels and transporters shaping calcium and exocytotic signals in chromafn cells [PDF]
This chapter focuses on calcium movements and their impact on exocytosis in adrenal medullary chromaffin cells (CCs). Upon depolarization, Ca2+ enters the cell through open plasmalemmal voltage-dependent calcium channels (Cav channels) driven by a large ...
García García, Antonio +4 more
core +1 more source
The involvement of TRP channels in bone homeostasis
Calcium and bone homeostasis are intimately related. On the one hand, bone relies on a sufficient supply of calcium to maintain its structural and mechanical properties and thus largely depends on calcium absorption in the intestine and calcium ...
Liesbet eLieben, Geert eCarmeliet
doaj +1 more source
Regulation of Presynaptic Calcium Channels by Synaptic Proteins
Calcium entry into nerve termini via voltage gated calcium channels is an essential step in neurotransmission. Consequently, second messenger regulation of calcium channel activity modulates synaptic activity.
Gerald W. Zamponi
doaj +1 more source
Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels [PDF]
Recent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy
Klugbauer, Norbert +19 more
core +2 more sources
Mitogens and Calcium Channels [PDF]
Mitogens and, in particular, growth factors can induce changes in free intracellular Ca2+ concentration by opening voltage-independent cationic channels, with different degrees of Ca2+ selectivity. Recent work has provided preliminary insights into the nature of these channels and their role in the control of cell cycle progression.
LOVISOLO D +3 more
openaire +2 more sources
Imaging large cohorts of single ion channels and their activity [PDF]
As calcium is the most important signaling molecule in neurons and secretory cells, amongst many other cell types, it follows that an understanding of calcium channels and their regulation of exocytosis is of vital importance.
Euan R. Brown +8 more
core +1 more source

