Results 11 to 20 of about 1,575,123 (299)

Structure and function of potassium and calcium channels [PDF]

open access: yes, 2005
In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
core   +7 more sources

ORAI Calcium Channels [PDF]

open access: yesPhysiology, 2017
In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on ...
Mohamed, Trebak, James W, Putney
openaire   +2 more sources

Tissue-specific expression of calcium channels [PDF]

open access: yes, 1993
The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Flockerzi, Veit   +3 more
core   +1 more source

The involvement of TRP channels in bone homeostasis

open access: yesFrontiers in Endocrinology, 2012
Calcium and bone homeostasis are intimately related. On the one hand, bone relies on a sufficient supply of calcium to maintain its structural and mechanical properties and thus largely depends on calcium absorption in the intestine and calcium ...
Liesbet eLieben, Geert eCarmeliet
doaj   +1 more source

TRPV5 and TRPV6 calcium-selective channels. [PDF]

open access: yes, 2017
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the ...
Hediger, Matthias   +3 more
core   +2 more sources

Regulation of Presynaptic Calcium Channels by Synaptic Proteins

open access: yesJournal of Pharmacological Sciences, 2003
Calcium entry into nerve termini via voltage gated calcium channels is an essential step in neurotransmission. Consequently, second messenger regulation of calcium channel activity modulates synaptic activity.
Gerald W. Zamponi
doaj   +1 more source

Calcium channels in lymphocytes [PDF]

open access: yesImmunology, 2001
On B and T lymphocytes, ligation of the antigen receptor (AgR) induces a biphasic Ca2+ response. In the initial phase there is a large elevation in the intracellular Ca2+ concentration as a consequence of Ca2+ release from intracellular stores. This is followed by a lower, but prolonged elevation that is dependent on extracellular Ca2+.1,2 This simple ...
G, Grafton, L, Thwaite
openaire   +2 more sources

Presynaptic calcium channels [PDF]

open access: yesNeuroscience Research, 2018
Presynaptic Ca2+ entry occurs through voltage-gated Ca2+ (CaV) channels which are activated by membrane depolarization. Depolarization accompanies neuronal firing and elevation of Ca2+ triggers neurotransmitter release from synaptic vesicles. For synchronization of efficient neurotransmitter release, synaptic vesicles are targeted by presynaptic Ca2 ...
openaire   +3 more sources

Ion Channels of Pituitary Gonadotrophs and Their Roles in Signaling and Secretion

open access: yesFrontiers in Endocrinology, 2017
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium concentration.
Stanko S. Stojilkovic   +2 more
doaj   +1 more source

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