Results 21 to 30 of about 1,814,083 (253)

Imaging large cohorts of single ion channels and their activity [PDF]

, 2013
As calcium is the most important signaling molecule in neurons and secretory cells, amongst many other cell types, it follows that an understanding of calcium channels and their regulation of exocytosis is of vital importance.
Euan R. Brown, Katia eHiersemenzel, Brown, Euan R; id_orcid, Katia Hiersemenzel, Rory R. Duncan, Duncan, Rory R, Hiersemenzel, Katia, Rory R Duncan, Euan R Brown   +8 more
core   +1 more source

Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes.

Frontiers in Immunology, 2013
In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou, Mithilesh K. Jha, Didi eMatza, Richard A. Flavell, Richard A. Flavell   +4 more
doaj   +1 more source

Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion [PDF]

, 2004
In many cell types agonist-receptor activation leads to a rapid and transient release of Ca(2+) from intracellular stores via activation of inositol 1,4,5 trisphosphate (InsP(3)) receptors (InsP(3)Rs).
Arnoult, Christophe, Cristiano Grasso, Treves, Susan, Ronjat, Michel, Mikoshiba, Katsuhiko, ARNOULT C, GRASSO C, TREVES, Susan Nella, Ducreux, Sylvie, DUCREUX S, Smida-Rezgui, Sophia, Franzini-Armstrong, Clara, MIKOSHIBA K, SCHRUM A, Sylvie Ducreux, Susan Treves, RONJAT M, Grasso, Cristiano, Zhu, Michael X., Zorzato, Francesco, SMIDA REZGUI S, Sophia Smida-Rezgui, MOCCAGATTA L, Zhu, Michael, Francesco Zorzato, Clara Franzini-Armstrong, Christophe Arnoult, Luca Moccagatta, Schrum, Adam, Michel Ronjat, ZHU MX, GIRARD T, Girard, Thierry, Katsuhiko Mikoshiba, Thierry Girard, FRANZINI ARMSTRONG C, Moccagatta, Luca, Michael X. Zhu, Adam Schrum, Treves S, Franzini-Armstrong C, Smida-Rezgui S, Zorzato F   +42 more
core   +1 more source

TRP channels in microglia: role in physiology and disease

Frontiers in Cellular Neuroscience, 2015
Microglia are responsible for modulating the cellular environment in the nervous system, where they have neuroprotective effects. In these cells has been reported the expression of different ion channels, including those belonging to the transient ...
Yolima P Torres
doaj   +1 more source

SLO BK Potassium Channels Couple Gap Junctions to Inhibition of Calcium Signaling in Olfactory Neuron Diversification. [PDF]

PLoS Genetics, 2016
The C. elegans AWC olfactory neuron pair communicates to specify asymmetric subtypes AWCOFF and AWCON in a stochastic manner. Intercellular communication between AWC and other neurons in a transient NSY-5 gap junction network antagonizes voltage ...
Amel Alqadah, Yi-Wen Hsieh, Jennifer A Schumacher, Xiaohong Wang, Sean A Merrill, Grethel Millington, Brittany Bayne, Erik M Jorgensen, Chiou-Fen Chuang   +8 more
doaj   +1 more source

Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels [PDF]

, 2013
Recent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy
Klugbauer, Norbert, Michael Nöldner, Nölder, Michael, Kristina Leuner (229356), Kristina Leuner, Schuwald, Anita M., Norbert Klugbauer, Michael Nöldner (408097), Anita M Schuwald, Walter E Müller, Norbert Klugbauer (408099), Leuner, Kristina, Walter E. Müller (229392), Thomas Wilmes, Schuwald, Anita Maria, Anita M. Schuwald (408096), Nöldner, Michael, Müller, Walter E., Wilmes, Thomas, Thomas Wilmes (408098), Klugbauer Norbert, Wilmes Thomas, Schuwald Anita M., Nöldner Michael, Leuner Kristina, Müller Walter E.   +25 more
core   +2 more sources

Functional Coupling of Cav2.3 and BK Potassium Channels Regulates Action Potential Repolarization and Short-Term Plasticity in the Mouse Hippocampus

Frontiers in Cellular Neuroscience, 2019
Voltage-gated ion channels are essential for signal generation and propagation in neurons and other excitable cells. The high-voltage activated calcium-channel Cav2.3 is expressed throughout the central and peripheral nervous system, and within CA1 ...
Jakob J. Gutzmann, Lin Lin, Dax A. Hoffman   +2 more
doaj   +1 more source

Developmental Regulation of Small-Conductance Ca²⁺-Activated K⁺ Channel Expression and Function in Rat Purkinje Neurons [PDF]

, 2002
Calcium transients play an important role in the early and later phases of differentiation and maturation of single neurons and neuronal networks. Small-conductance calcium-activated potassium channels of the SK type modulate membrane excitability and ...
Stocker, M, Pedarzani P., Stocker, M., Pedarzani, P, Cingolani, L., Cingolani L, Gymnopoulos, M., Boccaccio, A, Gymnopoulos M, Boccaccio A, Boccaccio, A., Cingolani, LA, Gymnopoulos, M, Pedarzani, P., Stocker M, Marco Gymnopoulos, Lorenzo A. Cingolani, Paola Pedarzani, Anna Boccaccio, Martin Stocker   +19 more
core   +1 more source

Role of calcium channels in the initiation and progression of osteoarthritis

Zhongguo linchuang yanjiu
Osteoarthritis is a chronic degenerative joint disease characterized primarily by the progressive breakdown of articular cartilage. Due to its complex pathogenesis，there is currently a lack of treatments that can effectively reverse the disease course ...
LIU Yizhan, SUN Chang, ZHU Yulei, CHEN Peng, HAN Tong, ZHANG Yunpeng   +5 more
doaj   +1 more source

Membrane Currents in Airway Smooth Muscle: Mechanisms and Therapeutic Implications

Canadian Respiratory Journal, 1997
Electrophysiological and pharmacological techniques were used to characterize the membrane conductance changes underlying spasmogen-evoked depolarization in airway smooth muscle (ASM).
Luke J Janssen
doaj   +1 more source