Results 31 to 40 of about 475,886 (304)
Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking [PDF]
, 2018 Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the ...
Chen, Xingjuan +10 more
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Membrane Currents in Airway Smooth Muscle: Mechanisms and Therapeutic Implications
Canadian Respiratory Journal, 1997 Electrophysiological and pharmacological techniques were used to characterize the membrane conductance changes underlying spasmogen-evoked depolarization in airway smooth muscle (ASM).
Luke J Janssen
doaj +1 more source
T-type calcium channel: a privileged gate for calcium entry and control of adrenal steroidogenesis
Frontiers in Endocrinology, 2016 Intracellular calcium plays a crucial role in modulating a variety of functions such as muscle contraction, hormone secretion, gene expression or cell growth. Calcium signaling has been however shown to be more complex than initially thought.
Michel Florian Rossier +1 more
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Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes. [PDF]
PLoS ONE, 2013 Calcium-activated potassium channels of the KCa1.1 class are known to regulate repolarization of action potential discharge through a molecular association with high voltage-activated calcium channels.
Renata Rehak +5 more
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MODULATION OF THE CGMP-GATED CHANNEL BY CALCIUM [PDF]
, 1995 Calcium acting through calmodulin has been shown to regulate the affinity of cyclic nucleotide-gated channels expressed in cell lines.
LAGNADO, L, SAGOO, MS
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Suramin-Induced Neurotoxicity: Preclinical Models and Neuroprotective Strategies
Molecules, 2018 Suramin is a trypan blue analogon originally developed to treat protozoan infections, which was found to have diverse antitumor effects. One of the most severe side effects in clinical trials was the development of a peripheral sensory-motor ...
David von der Ahe +5 more
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Cavβ surface charged residues contribute to the regulation of neuronal calcium channels
Molecular Brain, 2022 Voltage-gated calcium channels are essential regulators of brain function where they support depolarization-induced calcium entry into neurons. They consist of a pore-forming subunit (Cavα1) that requires co-assembly with ancillary subunits to ensure ...
Alexandra Tran-Van-Minh +2 more
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Store-operated calcium channels in skin
Frontiers in Physiology, 2022 The skin is a complex organ that acts as a protective layer against the external environment. It protects the internal tissues from harmful agents, dehydration, ultraviolet radiation and physical injury as well as conferring thermoregulatory control ...
Declan Manning +3 more
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A chloride channel in rat and human axons [PDF]
, 1991 Current recordings from single chloride channels were obtained from excised and cell-attached patches of rat and human axons. In rat axons the channels showed an outwardly rectifying current-voltage relationship with a slope conductance of 33 pS at ...
Baker +19 more
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Discrete stochastic modeling of calcium channel dynamics
, 1999 We propose a simple discrete stochastic model for calcium dynamics in living cells. Specifically, the calcium concentration distribution is assumed to give rise to a set of probabilities for the opening/closing of channels which release calcium thereby ...
Baer, Markus +3 more
core +1 more source