Results 31 to 40 of about 1,814,083 (253)

Store-operated calcium channels in skin

Frontiers in Physiology, 2022
The skin is a complex organ that acts as a protective layer against the external environment. It protects the internal tissues from harmful agents, dehydration, ultraviolet radiation and physical injury as well as conferring thermoregulatory control ...
Declan Manning, Declan Manning, Caroline Dart, Richard L Evans   +3 more
doaj   +1 more source

P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? [PDF]

, 2002
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic migraine indicates the potential involvement of dysfunctional ion channels in migraine.
Goadsby, PJ, Yolande E. Knight, Knight, Yolande E., Knight, YE, Goadsby, Peter J., Bartsch, Thorsten, Peter J. Goadsby, Kaube, Holger, Holger Kaube, Kaube, H, Thorsten Bartsch, Bartsch, T   +11 more
core   +1 more source

Pancreatic β Cell CaV Channels in Health and Disease

, 2022
Multiple types of voltage-gated calcium (CaV) channels including CaV1.2, CaV1.3, CaV2.1, CaV2.2, CaV2.3, CaV3.1, and CaV3.2 operate in electrically excitable β cells under both physiological and pathophysiological conditions.
Berggren, P-O, Yang, S-N, Yu, J, Zhao, K, Yang, G, Shi, Y   +5 more
core   +1 more source

T-type calcium channel: a privileged gate for calcium entry and control of adrenal steroidogenesis

Frontiers in Endocrinology, 2016
Intracellular calcium plays a crucial role in modulating a variety of functions such as muscle contraction, hormone secretion, gene expression or cell growth. Calcium signaling has been however shown to be more complex than initially thought.
Michel Florian Rossier, Michel Florian Rossier   +1 more
doaj   +1 more source

Functional implications of calcium permeability of the channel formed by pannexin 1. [PDF]

, 2006
Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap ...
Ivanov, Dmitry, V, Panchin, YV, Vanden Abeele, F, Fabien Vanden Abeele, Panchin, Yuri V, Gordienko, D, Yuri V. Panchin, Baranova, AV, Skryma, R, Baranova, Ancha, V, Skryma, Roman, Gordienko, Dmitri, Gabriel Bidaux, Beck, Benjamin, Ivanov, DV, Prevarskaya, N, Ancha V. Baranova, Baranova, Ancha V, Natalia Prevarskaya, Benjamin Beck, Ivanov, Dmitry V, Panchin, Yuri, Ivanov, Dimitri, Prevarskaya, Natalia, Vanden Abeele, Fabien, Bidaux, G, Bidaux, Gabriel, Dmitry V. Ivanov, Beck, B, Panchin, Yuri, V, Roman Skryma, Dmitri Gordienko   +31 more
core   +1 more source

Cavβ surface charged residues contribute to the regulation of neuronal calcium channels

Molecular Brain, 2022
Voltage-gated calcium channels are essential regulators of brain function where they support depolarization-induced calcium entry into neurons. They consist of a pore-forming subunit (Cavα1) that requires co-assembly with ancillary subunits to ensure ...
Alexandra Tran-Van-Minh, Michel De Waard, Norbert Weiss   +2 more
doaj   +1 more source

The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release [PDF]

, 2012
Hypothalamic magnocellular neurons release vasopressin and oxytocin not only from their axon terminals into the blood, but also from their somata and dendrites into the extracellular space of the brain, and this can be regulated independently ...
Tobin, Vicky, Vicky Tobin, Gareth Leng, Mike Ludwig, Gareth eLeng, Ludwig, Mike, Leng, Gareth, Vicky A. Tobin, Mike eLudwig   +8 more
core   +1 more source

Calcium activates SK channels in the intact human lens [PDF]

, 2003
Purpose: Apamin-sensitive, calcium-activated SK potassium channels have been implicated in schizophrenia and myotonic dystrophy (MD), and both conditions carry an increased risk of cataract.
Rhodes, Jeremy D., Collison, David J., Duncan, George   +2 more
core   +1 more source

The regulation role of calcium channels in mammalian sperm function: a narrative review with a focus on humans and mice [PDF]

PeerJ
Mammalian sperm are characterized as specialized cells, as their transcriptional and translational processes are largely inactive. Emerging researches indicate that Ca2+ serves as a crucial second messenger in the modulation of various sperm ...
Yebin Yang, Liu Yang, Xiaoqun Han, Kuaiying Wu, Guangquan Mei, Baojian Wu, Yimin Cheng   +6 more
doaj   +2 more sources

Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes. [PDF]

PLoS ONE, 2013
Calcium-activated potassium channels of the KCa1.1 class are known to regulate repolarization of action potential discharge through a molecular association with high voltage-activated calcium channels.
Renata Rehak, Theodore M Bartoletti, Jordan D T Engbers, Geza Berecki, Ray W Turner, Gerald W Zamponi   +5 more
doaj   +1 more source