Results 31 to 40 of about 257,064 (311)

Presynaptic Calcium Channel Open Probability and Changes in Calcium Influx Throughout the Action Potential Determined Using AP-Waveforms

open access: yesFrontiers in Synaptic Neuroscience, 2020
Action potentials arriving at a nerve terminal activate voltage-gated calcium channels and set the electrical driving force for calcium entry which affects the amount and duration of neurotransmitter release.
Matthew S. Scarnati   +6 more
doaj   +1 more source

Kv7 and Kv11 channels in myometrial regulation. [PDF]

open access: yes, 2013
Ion channels play a key role in defining myometrial contractility. Modulation of ion channel populations is proposed to underpin gestational changes in uterine contractility associated with the transition from uterine quiescence to active labour.
Tribe, Rachel M; id_orcid   +5 more
core   +1 more source

Functional Coupling of Cav2.3 and BK Potassium Channels Regulates Action Potential Repolarization and Short-Term Plasticity in the Mouse Hippocampus

open access: yesFrontiers in Cellular Neuroscience, 2019
Voltage-gated ion channels are essential for signal generation and propagation in neurons and other excitable cells. The high-voltage activated calcium-channel Cav2.3 is expressed throughout the central and peripheral nervous system, and within CA1 ...
Jakob J. Gutzmann   +2 more
doaj   +1 more source

Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]

open access: yes, 1990
In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Skott, O.   +5 more
core   +1 more source

T-type calcium channel: a privileged gate for calcium entry and control of adrenal steroidogenesis

open access: yesFrontiers in Endocrinology, 2016
Intracellular calcium plays a crucial role in modulating a variety of functions such as muscle contraction, hormone secretion, gene expression or cell growth. Calcium signaling has been however shown to be more complex than initially thought.
Michel Florian Rossier   +1 more
doaj   +1 more source

Membrane Currents in Airway Smooth Muscle: Mechanisms and Therapeutic Implications

open access: yesCanadian Respiratory Journal, 1997
Electrophysiological and pharmacological techniques were used to characterize the membrane conductance changes underlying spasmogen-evoked depolarization in airway smooth muscle (ASM).
Luke J Janssen
doaj   +1 more source

Calcium channels for endocytosis [PDF]

open access: yesThe Journal of Physiology, 2014
Exocytosis and endocytosis need to be tightly balanced to keep cell surface area constant. This is of particular relevance for presynaptic terminals, where endocytosis needs to compensate for the ongoing exocytosis of synaptic vesicle to ultimately guarantee reliable synaptic transmission.
openaire   +2 more sources

Vacuolar calcium channels [PDF]

open access: yesJournal of Experimental Botany, 2007
The central vacuole is the largest Ca2+ store in a mature plant cell. Ca2+ release from this store contributes to Ca2+-mediated intracellular signalling in a variety of physiological responses. However, the routes for vacuolar Ca2+ release are not well characterized.
I I, Pottosin, G, Schönknecht
openaire   +2 more sources

Suramin-Induced Neurotoxicity: Preclinical Models and Neuroprotective Strategies

open access: yesMolecules, 2018
Suramin is a trypan blue analogon originally developed to treat protozoan infections, which was found to have diverse antitumor effects. One of the most severe side effects in clinical trials was the development of a peripheral sensory-motor ...
David von der Ahe   +5 more
doaj   +1 more source

Store-operated calcium channels in skin

open access: yesFrontiers in Physiology, 2022
The skin is a complex organ that acts as a protective layer against the external environment. It protects the internal tissues from harmful agents, dehydration, ultraviolet radiation and physical injury as well as conferring thermoregulatory control ...
Declan Manning   +3 more
doaj   +1 more source

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