Results 11 to 20 of about 886,471 (280)
Function of TRP channels in monocytes/macrophages [PDF]
Frontiers in Immunology, 2023 The transient receptor potential channel (TRP channel) family is a kind of non- specific cation channel widely distributed in various tissues and organs of the human body, including the respiratory system, cardiovascular system, immune system, etc.
Jiangbo Wu +33 more
doaj +4 more sources
Cannabinoid Ligands Targeting TRP Channels [PDF]
Frontiers in Molecular Neuroscience, 2019 Transient receptor potential (TRP) channels are a group of membrane proteins involved in the transduction of a plethora of chemical and physical stimuli.
Chanté Muller +2 more
doaj +6 more sources
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 Pulmonary and systemic arterial hypertension are associated with profound alterations in Ca2+ homeostasis and smooth muscle cell proliferation. A novel class of non-selective cation channels, the transient receptor potential (TRP) channels, have emerged ...
Yuan, Jason X.-J. +2 more
core +3 more sources
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 “Transient receptor potential” cation channels (TRP channels) play a unique role as cell sensors, are involved in a plethora of Ca2+-mediated cell functions, and play a role as “gate-keepers” in many homeostatic processes such as Ca2+ and Mg2 ...
Bernd Nilius, Nilius, Bernd
core +5 more sources
Acta Pharmaceutica Sinica B, 2022 Transient receptor potential (TRP) channels are one primary type of calcium (Ca2+) permeable channels, and those relevant transmembrane and intracellular TRP channels were previously thought to be mainly associated with the regulation of cardiovascular ...
Tiecheng Zhong +7 more
doaj +3 more sources
Sensing with TRP channels [PDF]
Nature Chemical Biology, 2005 Drosophila melanogaster flies carrying the trp (transient receptor potential) mutation are rapidly blinded by bright light, because of the absence of a Ca2+-permeable ion channel in their photoreceptors.
Bernd Nilius +7 more
core +4 more sources
TRP Channels in Cancer: Signaling Mechanisms and Translational Approaches [PDF]
Biomolecules, 2023 Ion channels play a crucial role in a wide range of biological processes, including cell cycle regulation and cancer progression. In particular, the transient receptor potential (TRP) family of channels has emerged as a promising therapeutic target due ...
Matilde Marini +5 more
doaj +2 more sources
Neurosci Bull, 2023 Ischemic stroke is a devastating disease that affects millions of patients worldwide. Unfortunately, there are no effective medications for mitigating brain injury after ischemic stroke. TRP channels are evolutionally ancient biosensors that detect external stimuli as well as tissue or cellular injury.
Zong P +4 more
europepmc +3 more sources
TRP channels and breast cancer: the role of TRPs in the pathophysiological development [PDF]
Frontiers in Molecular BiosciencesTRP channels play important roles in regulating various physiological and pathological processes, including the progression of cancer. Several TRP channels mediate tumour development.
Yu Zhang +4 more
doaj +2 more sources
Sequence and structural conservation reveal fingerprint residues in TRP channels [PDF]
eLife, 2022 Transient receptor potential (TRP) proteins are a large family of cation-selective channels, surpassed in variety only by voltage-gated potassium channels.
Deny Cabezas-Bratesco +7 more
doaj +2 more sources