Results 1 to 10 of about 35,537 (259)

Combining mass spectrometry and genetic labeling in mice to report TRP channel expression [PDF]

MethodsX, 2022
Transient receptor potential (TRP) ion channels play important roles in fundamental biological processes throughout the body of humans and mice. TRP channel dysfunction manifests in different disease states, therefore, these channels may represent ...
Philipp Wartenberg, Femke Lux, Kai Busch, Claudia Fecher-Trost, Amanda Wyatt, Veit Flockerzi, Gabriela Krasteva-Christ, Ulrich Boehm, Petra Weissgerber   +8 more
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Responses to transient receptor potential (TRP) channel agonists in Chlamydomonas reinhardtii [PDF]

Biology Open, 2020
Pungent substances, such as capsaicin and gingerol, activate the transient receptor potential (TRP)-V1 channel and affect the feeding behaviors of animals.
Mamoru Wada, Itaru Kaizuka, Kenjiro Yoshimura   +2 more
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Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms [PDF]

eLife, 2020
The recent proliferation of published TRP channel structures provides a foundation for understanding the diverse functional properties of this important family of ion channel proteins.
Katherine E Huffer, Antoniya A Aleksandrova, Andrés Jara-Oseguera, Lucy R Forrest, Kenton J Swartz   +4 more
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A heteromeric TRP channel that functions as a WNT-activated G protein-coupled receptor [PDF]

Nature Communications
The human genome contains approximately 800 G protein-coupled receptors (GPCRs), all characterized by a common 7-transmembrane domain architecture. Here, we show that PKD1, an 11-transmembrane protein with a noncanonical transient receptor potential (TRP)
Emily P. Hardy, A. Nasim Haider, Maulin M. Patel, Vasyl Nesin, Hanh T. M. Hoang, Sandra E. Gostynska, William L. Berry, Augen A. Pioszak, Mohiuddin Ahmad, Stephen C. Parnell, Leonidas Tsiokas   +10 more
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Comprehensive Analysis of TRP Channel-Related Genes for Estimating the Immune Microenvironment, Prognosis, and Therapeutic Effect in Patients With Esophageal Squamous Cell Carcinoma [PDF]

Frontiers in Cell and Developmental Biology, 2022
The Nobel Prize in Physiology or Medicine for the year 2021 was awarded to Ardem Patapoutian and David Julius for their discoveries of temperature-sensitive receptors (TRP channels) and tactile receptors (Piezo channels), both of which were previously ...
Fangchao Zhao, Shaolin Gao, Xuebo Qin, Ren Niu, Zhirong Li, Chuan Wang, Shujun Li   +6 more
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Continuous glucose monitoring during pregnancy in healthy mice

Scientific Reports, 2021
During pregnancy, metabolic adaptations occur to maintain the balance between maternal and foetal growth, including increased insulin secretion and decreased insulin sensitivity. When the body fails to adjust, gestational diabetes mellitus develops.
Caroline Wuyts, Caroline Simoens, Silvia Pinto, Koenraad Philippaert, Rudi Vennekens   +4 more
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The Role of Membrane Lipids in Light-Activation of Drosophila TRP Channels

Biomolecules, 2022
Transient Receptor Potential (TRP) channels constitute a large superfamily of polymodal channel proteins with diverse roles in many physiological and sensory systems that function both as ionotropic and metabotropic receptors.
Rita Gutorov, Ben Katz, Elisheva Rhodes-Mordov, Rachel Zaguri, Tal Brandwine-Shemmer, Baruch Minke   +5 more
doaj   +1 more source

Function of TRP channels in monocytes/macrophages

Frontiers in Immunology, 2023
The transient receptor potential channel (TRP channel) family is a kind of non- specific cation channel widely distributed in various tissues and organs of the human body, including the respiratory system, cardiovascular system, immune system, etc.
Jiangbo Wu, Jiangbo Wu, Zhuo Li, Zhuo Li, Ya Deng, Ya Deng, Xianmin Lu, Xianmin Lu, Chen Luo, Chen Luo, Xingyi Mu, Xingyi Mu, Ting Zhang, Ting Zhang, Qi Liu, Qi Liu, Siqi Tang, Siqi Tang, Jiajing Li, Jiajing Li, Qimin An, Qimin An, Dongdong Fan, Dongdong Fan, Yiwei Xiang, Yiwei Xiang, Xianli Wu, Xianli Wu, Yanxia Hu, Yanxia Hu, Qian Du, Qian Du, Jingyu Xu, Rui Xie   +33 more
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Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels.

PLoS ONE, 2023
Transient receptor potential (TRP) channels are activated by various extracellular and intracellular stimuli and are involved in many physiological events.
Manae Tatsumi, Takayuki Kishi, Satoru Ishida, Hiroki Kawana, Akiharu Uwamizu, Yuki Ono, Kouki Kawakami, Junken Aoki, Asuka Inoue   +8 more
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TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases

Signal Transduction and Targeted Therapy, 2023
Transient receptor potential (TRP) channels are sensors for a variety of cellular and environmental signals. Mammals express a total of 28 different TRP channel proteins, which can be divided into seven subfamilies based on amino acid sequence homology ...
Miao Zhang, Yueming Ma, Xianglu Ye, Ning Zhang, Lei Pan, Bing Wang   +5 more
doaj   +1 more source