Results 41 to 50 of about 1,329,018 (250)
Diacylglycerol Activates the Light-Dependent Channel TRP in the Photosensitive Microvilli of Drosophila melanogaster Photoreceptors [PDF]
, 2014 Artículo de publicación ISIDrosophila light-dependent channels, TRP and TRPL, reside in the light-sensitive microvilli of the photoreceptor’s rhabdomere. Phospholipase C mediates TRP/TRPL opening, but the gating process remains unknown.
Bacigalupo Vicuña, Juan +10 more
core +1 more source
TRP Channels in Digestive Tract Cancers. [PDF]
, 2020 Cancers of the digestive tract are among the most prevalent types of cancer. These types of cancers are often diagnosed at a late stage, which results in a poor prognosis.
Borgström, Anna +11 more
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
TRPM3 in Brain (Patho)Physiology
Frontiers in Cell and Developmental Biology, 2021 Already for centuries, humankind is driven to understand the physiological and pathological mechanisms that occur in our brains. Today, we know that ion channels play an essential role in the regulation of neural processes and control many functions of ...
Katharina Held +2 more
doaj +1 more source
Advanced Science, EarlyView.This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang +13 more
wiley +1 more source
Advanced Science, EarlyView.A phosphorus‐modified single‐atom copper nanozyme delivering the IDO1 inhibitor 1‐methyl‐tryptophan enhances breast cancer radioimmunotherapy by simultaneously relieving hypoxia and inducing immunogenic cell death through dual enzyme activities while blocking tryptophan metabolism to suppress regulatory T cell function.
Wei Zhao +11 more
wiley +1 more source
TRP-channels as key integrators of lipid pathways in nociceptive neurons.
, 2016 TRP-channels are the most prominent family of ligand-gated ion channels for pain perception. In sensory neurons, TRPV1-V4, TRPA1 and TRPM8 are expressed and are responsible for the conversion of external stimuli to painful sensations.
Bennett, D.L.H. +3 more
core +2 more sources
A structural view of ligand-dependent activation in thermoTRP channels
Frontiers in Physiology, 2014 Transient Receptor Potential (TRP) proteins are a large family of ion channels, grouped intoseven sub-families. Although great advances have been made regarding the activation andmodulation of TRP channel activity, detailed molecular mechanisms governing
Ximena eSteinberg +3 more
doaj +1 more source
Identification of intracellular and plasma membrane calcium channel homologues in pathogenic parasites. [PDF]
PLoS ONE, 2011 Ca(2+) channels regulate many crucial processes within cells and their abnormal activity can be damaging to cell survival, suggesting that they might represent attractive therapeutic targets in pathogenic organisms.
David L Prole, Colin W Taylor
doaj +1 more source
TRP-1 and TRP-2 are required for head steering locomotion.
, 2018 (A) Schematic of the SMD neurons in C. elegans and the values analyzed during forward movement. (B) A phylogenetic tree of the TRPC subfamily channels. (C) The genomic locations (above) and structures (below) of the trp-1 and trp-2 genes.
Jinmahn Kim (787021) +9 more
core +1 more source