Results 31 to 40 of about 1,329,018 (250)
BMC Neuroscience, 2013 Background Somatosensory nerve fibres arising from cell bodies within the trigeminal ganglia (TG) in the head and from a string of dorsal root ganglia (DRG) located lateral to the spinal cord convey endogenous and environmental stimuli to the central ...
Vandewauw Ine +2 more
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Frontiers in Immunology, 2022 BackgroundTransient Receptor Potential (TRP) channel is a kind of channel protein widely distributed in peripheral and central nervous system. They can be regulated by natural aromatic substances and serve as a therapeutic target for many diseases ...
Gujie Wu +7 more
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Advanced Science, 2020 Transient receptor potential (TRP) channels are emerging drug targets, and TRP channel modulators possess therapeutic potential for many indications. However, there is a lack of intellectual and robust screening assays against TRP channels utilizing the ...
Xiaoni Ai +7 more
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Structure-function relationship of the TRP channel superfamily [PDF]
, 2006 Transient receptor potential (TRP) channels are involved in the perception of a wide range of physical and chemical stimuli, including temperature and osmolarity changes, light, pain, touch, taste and pheromones, and in the initiation of cellular ...
Owsianik, Grzegorz +3 more
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X-ray crystallography of TRP channels
Channels, 2018 Transient receptor potential (TRP) ion channels are molecular sensors of a large variety of stimuli including temperature, mechanical stress, voltage, small molecules including capsaicin and menthol, and lipids such as phosphatidylinositol 4,5 ...
Appu K. Singh +3 more
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TRP Channels Entering the Structural Era [PDF]
, 2008 Transient receptor potential (TRP) channels are important in many neuronal and non-neuronal physiological processes. The past 2 years have seen much progress in the use of structural biology techniques to elucidate molecular mechanisms of TRP channel ...
Gaudet, Rachelle, Rachelle Gaudet
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Negative inotropic and dromotropic actions of SiO2 nanoparticles on isolated rat hearts: Effects on Na+ and Ca2+ currents [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2016 Context: SiO2 nanoparticles (NP) are widely used in the industry and in varied biotechnological and medical applications. However, epidemiological studies suggest that pollution with fine particles (in which silica is an inorganic component) may increase
Julio Alvarez-Collazo +5 more
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Ligand-Binding Sites in Vanilloid-Subtype TRP Channels
Frontiers in Pharmacology, 2022 Vanilloid-subfamily TRP channels TRPV1-6 play important roles in various physiological processes and are implicated in numerous human diseases. Advances in structural biology, particularly the “resolution revolution” in cryo-EM, have led to breakthroughs
Maria V. Yelshanskaya +1 more
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, 2013 Users can represent the TRP channel PPI data as a network using the Cytoscape program. (A) The PPI network consists of the relations between TRP channels and their interacting proteins.
Soo-Yong Shin (303252) +8 more
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Functional Role of Transient Receptor Potential Channels in Immune Cells and Epithelia
Frontiers in Immunology, 2018 Transient receptor potential (TRP) ion channels are widely expressed in several tissues throughout the mammalian organism. Originally, TRP channel physiology was focusing on its fundamental meaning in sensory neuronal function.
Mohammad Khalil +6 more
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