Results 1 to 10 of about 40,616 (253)

Beneficial Effects of Capsaicin in Disorders of the Central Nervous System

open access: yesMolecules, 2022
Capsaicin is a natural compound found in chili peppers and is used in the diet of many countries. The important mechanism of action of capsaicin is its influence on TRPV1 channels in nociceptive sensory neurons.
Michał Pasierski, Bartłomiej Szulczyk
exaly   +3 more sources

Capsaicin for Rhinitis [PDF]

open access: yesCurrent Allergy and Asthma Reports, 2016
Rhinitis is a multifactorial disease characterized by symptoms of sneezing, rhinorrhea, postnasal drip, and nasal congestion. Non-allergic rhinitis is characterized by rhinitis symptoms without systemic sensitization of infectious etiology. Based on endotypes, we can categorize non-allergic rhinitis into an inflammatory endotype with usually ...
Fokkens, Wytske   +2 more
openaire   +4 more sources

Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases

open access: yesMolecules, 2016
Capsaicin is the most predominant and naturally occurring alkamide found in Capsicum fruits. Since its discovery in the 19th century, the therapeutic roles of capsaicin have been well characterized. The potential applications of capsaicin range from food
Shaherin Basith   +2 more
exaly   +3 more sources

Hydroalcoholic extracts of three Artemisia species attenuate dental pulp pain and pain-related abnormal feeding behavior of rats [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2022
This study considered the therapeutic efficacy of three different Artemisia species extracts on capsaicin-induced dental pulp pain and pain-associated changes in feeding behaviors in adult male Wistar rats.
Jahangir Haghani   +6 more
doaj   +1 more source

The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells

open access: yesPharmaceutics, 2022
The natural bioactive compound capsaicin has been reported to have anticancer activity, although the underlying mechanism of action has not been completely clarified.
Belén G. Sánchez   +3 more
doaj   +1 more source

Immunomodulatory and anti-oxidative effect of the direct TRPV1 receptor agonist capsaicin on Schwann cells

open access: yesJournal of Neuroinflammation, 2020
Background Only few studies describe the impact of nutritive factors on chronic inflammatory demyelinating polyneuropathy (CIDP), an inflammatory disease of the peripheral nervous system.
Thomas Grüter   +9 more
doaj   +1 more source

Nitro Capsaicin Suppressed Microglial Activation and TNF-α-Induced Brain Microvascular Endothelial Cell Damage

open access: yesBiomedicines, 2022
Chronically activated microglia and brain vascular damage are major causes of neuroinflammation. The aim of this study was to determine the anti-inflammatory effects of nitro capsaicin, a newly modified capsaicin with less irritating characteristics ...
Sopana Jamornwan   +6 more
doaj   +1 more source

Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway. [PDF]

open access: yesPLoS ONE, 2010
Small cell lung cancer (SCLC) is characterized by rapid progression and low survival rates. Therefore, novel therapeutic agents are urgently needed for this disease. Capsaicin, the active ingredient of chilli peppers, displays anti-proliferative activity
Kathleen C Brown   +7 more
doaj   +1 more source

Capsaicin, a Phytochemical From Chili Pepper, Alleviates the Ultraviolet Irradiation-Induced Decline of Collagen in Dermal Fibroblast via Blocking the Generation of Reactive Oxygen Species

open access: yesFrontiers in Pharmacology, 2022
Capsaicin, a major ingredient in chili pepper, has broad pharmaceutical applications, including relieving pain, anti-inflammation, and treating psoriasis.
Qiyun Wu   +14 more
doaj   +1 more source

The Effect of Capsaicin on Salivary Gland Dysfunction

open access: yesMolecules, 2016
Capsaicin (trans-8-methyl-N-vanilyl-6-nonenamide) is a unique alkaloid isolated from hot chili peppers of the capsicum family. Capsaicin is an agonist of transient receptor potential vanilloid subtype 1 (TRPV1), which is expressed in nociceptive sensory ...
Yong-Hwan Shin   +2 more
doaj   +1 more source

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