Results 11 to 20 of about 29,187 (199)
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
The Effect of Capsaicin on Salivary Gland Dysfunction
Molecules, 2016 Capsaicin (trans-8-methyl-N-vanilyl-6-nonenamide) is a unique alkaloid isolated from hot chili peppers of the capsicum family. Capsaicin is an agonist of transient receptor potential vanilloid subtype 1 (TRPV1), which is expressed in nociceptive sensory ...
Yong-Hwan Shin +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2017 We investigated whether capsaicin modulated synaptic transmission to hypoglossal motor neurons (HMNs) by acting on transient receptor potential vanilloid type 1 (TRPV1) receptors.
Prajwal P. Thakre, Mark C. Bellingham
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Capsaicin Potently Blocks Salmonella typhimurium Invasion of Vero Cells
Antibiotics, 2022 Salmonella typhimurium (S. typhimurium) is one of the major food and waterborne bacteria that causes several health outbreaks in the world. Although there are few antibiotics against this bacterium, some of these drugs are challenged with resistance and ...
Joseph A. Ayariga +3 more
doaj +1 more source
Natural Product Communications, 2021 Capsaicin, an ingredient of green and red bell peppers, shows anticancer activity in several malignant cell lines. Thymidylate synthase (TS) is a well-validated anticancer drug target in non-small cell lung cancer (NSCLC) cells.
Chun-Liang Tung +10 more
doaj +1 more source
Effects of Capsaicin on Biomimetic Membranes
Biomimetics, 2019 Capsaicin is a natural compound that produces a warm sensation and is known for its remarkable medicinal properties. Understanding the interaction between capsaicin with lipid membranes is essential to clarify the molecular mechanisms behind its ...
Neha Sharma +5 more
doaj +1 more source
Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases
Molecules, 2016 Capsaicin is the most predominant and naturally occurring alkamide found in Capsicum fruits. Since its discovery in the 19th century, the therapeutic roles of capsaicin have been well characterized. The potential applications of capsaicin range from food
Shaherin Basith +3 more
doaj +1 more source
Resilience to capsaicin-induced mitochondrial damage in trigeminal ganglion neurons
Molecular Pain, 2020 Capsaicin is an agonist of transient receptor potential cation channel subfamily V member 1 (TRPV1). Strong TRPV1 stimulation with capsaicin causes mitochondrial damage in primary sensory neurons.
Mamoru Shibata +7 more
doaj +1 more source
The Mysteries of Capsaicin-Sensitive Afferents
Frontiers in Physiology, 2020 A fundamental subdivision of nociceptive sensory neurons is named after their unique sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin-sensitive afferents.
Michael J. M. Fischer +2 more
doaj +1 more source
Effects of Capsaicin on Adipogenic Differentiation in Bovine Bone Marrow Mesenchymal Stem Cell [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 Capsaicin is a major constituent of hot chili peppers that influences lipid metabolism in animals. In this study, we explored the effects of capsaicin on adipogenic differentiation of bovine bone marrow mesenchymal stem cells (BMSCs) in a dose- and time ...
Jin Young Jeong +8 more
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